Kurt E. Kwast
University of Colorado Boulder
18 Papers
240 Citations
Kurt E. Kwast is an academic researcher from University of Colorado Boulder. The author has contributed to research in topics: Gene & Saccharomyces cerevisiae. The author has an hindex of 16, co-authored 18 publications. Previous affiliations of Kurt E. Kwast include Urbana University & University of Illinois at Urbana–Champaign.
Chat about Author
Papers
Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes
TL;DR: It is found that carbon monoxide completely blocks the anoxia-induced expression of two hypoxic genes, OLE1 and CYC7, partially blocks the induction of a third gene, COX5b, and has no effect on the expression of other hypoxic or aerobic genes.
178
Top-Down Proteomics on a Chromatographic Time Scale Using Linear Ion Trap Fourier Transform Hybrid Mass Spectrometers
Bryan A. Parks,Lihua Jiang,Paul M. Thomas,Craig D. Wenger,Michael J. Roth,Michael T. Boyne,Patricia V. Burke,Kurt E. Kwast,Neil L. Kelleher +8 more
TL;DR: This is the first demonstration of top-down proteomics (i.e., many identifications) on linear ion trap Fourier transform (LTQ FT) systems using high-resolution MS/MS data obtained on a chromatographic time scale.
131
Metabolic-state-dependent remodeling of the transcriptome in response to anoxia and subsequent reoxygenation in Saccharomyces cerevisiae
TL;DR: A comprehensive genomic analysis of the temporal response of yeast to anaerobiosis and subsequent aerobic recovery is conducted to reveal metabolic-state (galactose versus glucose)-dependent differences in gene network activity and function.
101
Function and Expression of Flavohemoglobin in Saccharomyces cerevisiae EVIDENCE FOR A ROLE IN THE OXIDATIVE STRESS RESPONSE
Xiao Jian Zhao,Desmond C. Raitt,Patricia V. Burke,Amy E. Clewell,Kurt E. Kwast,Robert O. Poyton +5 more
TL;DR: Findings suggest that YHb plays a role in the oxidative stress response in yeast, consistent with the observation that conditions that promote oxidative stress also enhance expression of YHB1.
94
Dynamical remodeling of the transcriptome during short-term anaerobiosis in Saccharomyces cerevisiae: differential response and role of Msn2 and/or Msn4 and other factors in galactose and glucose media.
TL;DR: Overall, this study reveals that the acute withdrawal of oxygen can invoke a metabolic state-dependent “stress response” but that acclimatization to oxygen deprivation is a relatively slow process involving complex changes primarily in heme-regulated gene networks.
92