Kun Wang
Wayne State University
9 Papers
188 Citations
Kun Wang is an academic researcher from Wayne State University. The author has contributed to research in topics: Chemical shift & Equilibrium constant. The author has an hindex of 7, co-authored 9 publications.
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Papers
Inhibition of Papain by S-Nitrosothiols FORMATION OF MIXED DISULFIDES
TL;DR: Results suggest that inactivation of papain byS-nitrosothiols is due to a direct attack of the highly reactive thiolate in the enzyme active site on the sulfur of S-nitrosos to form a mixed disulfide between the inactivator and papain.
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Equilibrium and kinetics studies of transnitrosation between S-nitrosothiols and thiols.
TL;DR: The obtained Gibbs free energy, enthalpy and entropy data indicated that NO transfer reactions from SNAP to four thiols are exothermic with entropy loss.
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New chemical and biological aspects of S-nitrosothiols.
TL;DR: This review focuses on the latest discoveries pertaining to the biological functions of S-nitrosothiols and the recent research progress in the chemical properties and biomedical applications of RSNOs.
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Inhibition of protein tyrosine phosphatases by low-molecular-weight S-nitrosothiols and S-nitrosylated human serum albumin
Ming Xian,Kun Wang,Xinchao Chen,Yongchun Hou,Andrea McGill,Xi Chen,Bo Zhou,Zhong Yin Zhang,Jin Pei Cheng,Peng George Wang +9 more
TL;DR: Both single- and poly-S-nitrosylated human serum albumin show good inhibitory ability to Yersinia PTPase, indicating a possibility that S-nitrosothiols in vivo may function as an inhibitor for a variety of cysteine-dependent enzymes.
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