Kun Wang
Fudan University
9 Papers
Kun Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Acclimatization. The author has an hindex of 2, co-authored 4 publications.
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Papers
Physiological, hematological and biochemical factors associated with high-altitude headache in young Chinese males following acute exposure at 3700 m.
Kun Wang,Menghan Zhang,Yi Li,Yi Li,Weilin Pu,Yanyun Ma,Yanyun Ma,Yi Wang,Xiaoyu Liu,Longli Kang,Xiaofeng Wang,Jiucun Wang,Jiucun Wang,Bin Qiao,Li Jin,Li Jin +15 more
TL;DR: It is confirmed that higher HR, lower SpO2 are independent risk factors for HAH, and at both 50 m and 3700 m, lower BUN is a novel independent risk factor forHAH, providing new insights for understanding the pathological mechanisms.
Using Composite Phenotypes to Reveal Hidden Physiological Heterogeneity in High-Altitude Acclimatization in a Chinese Han Longitudinal Cohort
Yi Li,Yanyun Ma,Kun Wang,Menghan Zhang,Yi Wang,Xiaoyu Liu,Meng Hao,Xianhong Yin,Meng Liang,Hui Zhang,Xiaofeng Wang,Xingdong Chen,Yao Zhang,Wenyuan Duan,Longli Kang,Bin Qiao,Jiucun Wang,Jiucun Wang,Li Jin,Li Jin +19 more
- 01 Feb 2021
TL;DR: This study developed a strategy that combines both spectral clustering and partial least squares path modeling (PLSPM) to define composite phenotypes based on a cohort study of 883 Chinese Han males that fit better than single trait-based Model 1 in all measurement indices.
Thickened Retinal Nerve Fiber Layers Associated With High-Altitude Headache
Xianhong Yin,Yi Li,Yanyun Ma,Yuan Xie,Kun Wang,Dayan Sun,Xiaoyu Liu,Meng Hao,Meng Liang,Shixuan Zhang,Yuanyi Guo,Li Jin,Ningli Wang,Jiucun Wang +13 more
TL;DR: The high-altitude environment can increase RNFL thickness at ONH and the ratios of mean thickness, inferior area, and nasal area correlated positively with HAH, which provides new insights for understanding of the underlying pathological mechanisms of high-Altitude retinopathy (HAR).
6
Presence of Rare Variants is Associated with Poorer Survival in Chinese Patients with Amyotrophic Lateral Sclerosis
Si-qi Dong,Xianhong Yin,Kun Wang,Wen-bo Yang,Jiatong Li,Yi Wang,Yan-ni Zhou,Xiaoni Liu,Jiucun Wang,Xiangjun Chen +9 more
TL;DR: It is suggested that rare variants could exert a negative prognostic effect, thereby supporting the oligogenic inheritance of ALS.
4
Using composite phenotypes to reveal hidden physiological heterogeneity and model oxygen saturation variation of high altitude acclimatization in a Chinese Han longitudinal cohort
Yi Li,Yi Wang,Menghan Zhang,Yanyun Ma,Kun Wang,Xiaoyu Liu,Meng Hao,Chang Sun,Xiaofeng Wang,Xingdong Chen,Yao Zhang,Wenyuan Duan,Longli Kang,Bin Qiao,Jiucun Wang,Li Jin +15 more
TL;DR: A new strategy which combines both spectral clustering and Partial Least Squares Path Modeling to define and apply composite phenotypes can be considered as a general strategy of complex traits research, which may also shed light on genetic loci discovery and phenome analyses.