16 Papers
2 Citations
Kun Li is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 5, co-authored 8 publications.
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Papers
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats.
Xuankang Wang,Xin Li,Xiaoshuang Zuo,Zhuowen Liang,Ding Tan,Kun Li,Yangguang Ma,Penghui Li,Zhijie Zhu,Cheng Ju,Zhihao Zhang,Zhiwen Song,Huilin Quan,Jiawei Zhang,Xueyu Hu,Zhe Wang +15 more
TL;DR: In this article, the authors investigated whether photobiomodulation (PBM) can promote functional recovery by reducing neuroinflammation after spinal cord injury (SCI), but little is known about the underlying mechanism.
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Attenuation of the inflammatory response and polarization of macrophages by photobiomodulation
Kun Li,Zhuowen Liang,Jiawei Zhang,Xiaoshuang Zuo,Jiakai Sun,Qiao Zheng,Jiwei Song,Ding Tan,Xueyu Hu,Zhe Wang +9 more
TL;DR: Results suggest that PBM can successfully modulate inflammation and polarization in classically activated BMDMs, providing a theoretical basis to support wider clinical application of PBM in the treatment of SCI.
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Photobiomodulation Attenuates Neurotoxic Polarization of Macrophages by Inhibiting the Notch1-HIF-1α/NF-κB Signalling Pathway in Mice With Spinal Cord Injury
Yangguang Ma,Penghui Li,Cheng Ju,Xiaoshuang Zuo,Xin Li,Tan Ding,Zhuowen Liang,Jiawei Zhang,Kun Li,Xuan-Kang Wang,Zhijie Zhu,Zhihao Zhang,Zhiwen Song,Huili Quan,Xueyu Hu,Zhe Wang +15 more
TL;DR: PBM promoted better motor recovery after SCI in mice by inhibiting the neurotoxic polarization of macrophages and the release of inflammatory mediators by acting on the Notch1-HIF-1α/NF-κB Signalling Pathway.
Photobiomodulation Therapy Inhibit the Activation and Secretory of Astrocytes by Altering Macrophage Polarization
Jiakai Sun,Jiawei Zhang,Kun Li,Qiao Zheng,Jiwei Song,Zhuowen Liang,Ding Tan,Lin Qiao,Jianxin Zhang,Xueyu Hu,Zhe Wang +10 more
TL;DR: Results demonstrate that PBM may regulate the interaction between macrophages and astrocytes after spinal cord injury, which inhibited the formation of glial scar.
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Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36
Zhijie Zhu,Xin Li,Xuan-Kang Wang,Xiaoshuang Zuo,Yangguang Ma,Zhuowen Liang,Zhihao Zhang,Zhiwen Song,Tan Ding,Cheng Ju,Penghui Li,Kun Li,Jiawei Zhang,Huilin Quan,Zhe Wang,Xueyu Hu +15 more
TL;DR: Zhang et al. as mentioned in this paper demonstrated that photobiomodulation (PBM) could promote the transfer process, thus augmenting the therapeutic effect of mitochondrial transplantation, and further verified that Cx36 mediated the transfer of mitochondria into neurons.
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