Kuei-Tien Chen
Chang Gung University
17 Papers
82 Citations
Kuei-Tien Chen is an academic researcher from Chang Gung University. The author has contributed to research in topics: Autoantibody & Phospholipid scramblase. The author has an hindex of 10, co-authored 17 publications.
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Papers
Multiple serological biomarkers for colorectal cancer detection
Chung-Chuan Chan,Chung-Wei Fan,Yung-Bin Kuo,Yung-Bin Kuo,Yu-Han Chen,Pi-Yueh Chang,Kuei-Tien Chen,Ray-Ping Hung,Err-Cheng Chan +8 more
TL;DR: Results collectively indicated that combined detection of serum autoantibody profiles against a panel of colorectal tumor‐associated antigens and the analysis of carcinoembryonic antigen provides a promising diagnostic biomarker for coloreCTal cancer, particularly among early‐stage patients.
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Identification of Phospholipid Scramblase 1 as a Biomarker and Determination of Its Prognostic Value for Colorectal Cancer
Yung-Bin Kuo,Chung-Chuan Chan,C. Allen Chang,C. Allen Chang,Chung-Wei Fan,Ray-Ping Hung,Ya-Shu Hung,Kuei-Tien Chen,Jau-Song Yu,Yu-Sun Chang,Err-Cheng Chan +10 more
TL;DR: Examination of the expression of phospholipid scramblase 1 in tumor tissues and plasma specimens of patients with colorectal cancer and its association with clinical parameters revealed that elevated PLSCR1 expression indicated a poor prognosis for CRC, and the plasma levels were significantly elevated in patients with early stage CRC compared with healthy individuals.
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Identifying differentially expressed genes associated with metastasis of follicular thyroid cancer by cDNA expression array.
TL;DR: The cDNA expression array technology is utilized herein to profile differentially expressed genes from metastatic human follicular thyroid carcinoma and reveal new tumor markers as well as target genes for therapeutic intervention.
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Combined analysis of survivin autoantibody and carcinoembryonic antigen biomarkers for improved detection of colorectal cancer
TL;DR: A positive association between autoantibodies against survivin and preoperative CEA concentrations in sera of patients with CRCs was established and the results suggest that analysis of both parameters would assist in screening Patients with CRC.
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Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo
Chung-Wei Fan,Chun-Yu Chen,Kuei-Tien Chen,Chia-Rui Shen,Yung-Bin Kuo,Ya-Shan Chen,Yeh-Pin Chou,Yeh-Pin Chou,Wei-Shan Wei,Err-Cheng Chan +9 more
TL;DR: Treating CRC cells with NP1 in vitro and in vivo decreased cell proliferation, anchorage-independent growth, migration, and invasion, and may serve as a potential therapeutic target for CRC.