Kuan Yu
Fudan University
11 Papers
1 Citations
Kuan Yu is an academic researcher from Fudan University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 4, co-authored 7 publications.
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Papers
Poor clinical outcomes of intratumoral dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin-positive macrophages associated with immune evasion in gastric cancer.
Xin Liu,Yifan Cao,Ruochen Li,Yong Gu,Yifan Chen,Yangyang Qi,Kunpeng Lv,Jieti Wang,Kuan Yu,Chao Lin,Hao Liu,Heng Zhang,Hongyong He,Lingli Chen,Peipei Zhang,Zhenbin Shen,Jing Qin,Yihong Sun,He Li,Hua Huang,Weijuan Zhang,Jiejie Xu +21 more
TL;DR: It is demonstrated that high intratumoral DC-SIGN+ macrophages infiltration predicted poor OS and inferior therapeutic responsiveness to fluorouracil-based ACT in patients with gastric cancer.
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Clinical Outcomes and Immune Metrics in Intratumoral Basophil-Enriched Gastric Cancer Patients.
Xudong He,Yifan Cao,Yun Gu,Hanji Fang,Jieti Wang,Xin Liu,Kunpeng Lv,Kuan Yu,Yuchao Fei,Chao Lin,Hao Liu,Heng Zhang,He Li,Jiejie Xu,Ruochen Li,Hongyong He +15 more
TL;DR: In this paper, the authors investigated the postoperative prognostic and predictive significance of basophils to survival outcomes and chemotherapeutic responsiveness in resectable gastric cancer.
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Lauren classification identifies distinct prognostic value and functional status of intratumoral CD8+ T cells in gastric cancer.
Ruochen Li,Heng Zhang,Yifan Cao,Xin Liu,Yifan Chen,Yangyang Qi,Jieti Wang,Kuan Yu,Chao Lin,Hao Liu,Hongyong He,He Li,Lingli Chen,Zhenbin Shen,Jing Qin,Weijuan Zhang,Yihong Sun,Jiejie Xu +17 more
TL;DR: It was found that the density, prognostic significance and functional status of intratumoral CD8+ T cells varied with Lauren subtypes in gastric cancer, which indicated Lauren classification might be a potential therapeutic marker, and should be considered in therapeutic decisions, especially immunotherapeutic eligibility.
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Blockade of V‐domain immunoglobulin suppressor of T‐cell activation reprograms tumour‐associated macrophages and improves efficacy of PD‐1 inhibitor in gastric cancer
Yifan Cao,Kuan Yu,Zihao Zhang,Yun Gu,Yichao Gu,Wandi Li,Weijuan Zhang,Zhenbin Shen,Jiejie Xu,Jing Qin +9 more
TL;DR: Investigation of the clinical significance and potential mechanism of VISTA in affecting gastric cancer patients’ survival and immunotherapeutic responsiveness revealed that VISTA was an immune‐checkpoint associated with immunotherapeutic resistance.
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