Koustav Sarkar
SRM University
67 Papers
79 Citations
Koustav Sarkar is an academic researcher from SRM University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 18, co-authored 34 publications. Previous affiliations of Koustav Sarkar include Boston Children's Hospital & Chittaranjan National Cancer Institute.
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Papers
Nuclear Role of WASp in the Pathogenesis of Dysregulated TH1 Immunity in Human Wiskott-Aldrich Syndrome
Matthew D. Taylor,Sanjoy Sadhukhan,Ponnappa Kottangada,Archana Ramgopal,Koustav Sarkar,Sheryl D’Silva,Annamalai Selvakumar,Fabio Candotti,Yatin M. Vyas +8 more
TL;DR: A nuclear role for WASp is discovered in the transcriptional regulation of the TH1 regulator gene TBX21 at the chromatin level, revealing a previously unappreciated role of WASp in the epigenetic control of TH1 cell fate choice in the human TH cell genome.
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HDAC inhibitors: Targets for tumor therapy, immune modulation and lung diseases
TL;DR: In this article , a review of the use of histone deacetylases (HDACs) inhibitors in the treatment of chronic obstructive pulmonary disease and lung cancer is presented.
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Neuropeptide Y in the forebrain of the adult male cichlid fish Oreochromis mossambicus: distribution, effects of castration and testosterone replacement.
TL;DR: It is suggested that the NPY‐immunoreactive elements that respond to castration and testosterone replacement may serve as the substrate for processing the positive feedback action of the steroid hormone.
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Nuclear Role of WASp in Gene Transcription Is Uncoupled from Its ARP2/3-Dependent Cytoplasmic Role in Actin Polymerization
Sanjoy Sadhukhan,Koustav Sarkar,Matthew D. Taylor,Fabio Candotti,Yatin M. Vyas,Yatin M. Vyas +5 more
TL;DR: An ARP2/3:VCA-independent function of nuclear-WASp in TH1 gene activation that is uncoupled from its cytoplasmic role in actin polymerization is unveiled.
Neem Leaf Glycoprotein Induces Perforin-mediated Tumor Cell Killing by T and NK Cells Through Differential Regulation of IFNγ Signaling
Anamika Bose,Krishnendu Chakraborty,Koustav Sarkar,Shyamal Goswami,Tathagata Chakraborty,Smarajit Pal,Rathindranath Baral +6 more
TL;DR: It is concluded that NLGP might be effective to recover the suppressed cytotoxic functions of NK and T cells from head and neck squamous cell carcinoma patients.
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