Komal Rani
All India Institute of Medical Sciences
23 Papers
21 Citations
Komal Rani is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 6, co-authored 13 publications. Previous affiliations of Komal Rani include Amity University.
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Papers
The Evolving Landscape of Exosomes in Neurodegenerative Diseases: Exosomes Characteristics and a Promising Role in Early Diagnosis.
Simran Rastogi,Vaibhav Sharma,Prahalad Singh Bharti,Komal Rani,Gyan Modi,Fredrik Nikolajeff,Saroj Kumar +6 more
TL;DR: Exosomes are reviewed, their biogenesis, composition, and role in neurodegenerative diseases, and details for their characterization through an array of available techniques are provided and a novel field of salivary exosomes as a potential candidate for early diagnosis in neuro degenerative diseases is shed light.
135
Characterization of protein extracts from different types of human teeth and insight in biomineralization
Vaibhav Sharma,Alagiri Srinivasan,Ajoy Roychoudhury,Komal Rani,Mitali Tyagi,Kapil Dev,Fredrik Nikolajeff,Saroj Kumar +7 more
TL;DR: The present study describes an efficient method for isolation and purification of protein extracts from four types of human teeth i.e. molar, premolar, canine, and incisor as these extracts imitate the in vivo tooth mineralization.
Aminoglycoside induced nephrotoxicity: molecular modeling studies of calreticulin-gentamicin complex.
TL;DR: Detailed structural insight is provided of the calreticulin-gentamicin complex by molecular modeling and the binding of the drug in the presence of explicit solvent was analyzed by molecular dynamics simulation, strongly implicate gentamicin as a competitive inhibitor of sugar binding with cal reticulin.
16
Identification of annotated metabolites in the extract of Centella asiatica
Komal Rani,Mitali Tyagi,Akanksha Singh,Vairamani Shanmugam,Annaian Shanmugam,Manoj Pillai,Alagiri Srinivasan +6 more
TL;DR: Both beneficial and harmful compounds are reported in the methanol extract of Centella asiatica, suggesting that the harmful compounds can be removed to yield safe medicines from CA.