Koji Kono
Fukushima Medical University
268 Papers
1.6K Citations
Koji Kono is an academic researcher from Fukushima Medical University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 50, co-authored 233 publications. Previous affiliations of Koji Kono include National University of Singapore & University of Yamanashi.
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Papers
Consensus guidelines for the detection of immunogenic cell death
Oliver Kepp,Laura Senovilla,Ilio Vitale,Erika Vacchelli,Sandy Adjemian,Patrizia Agostinis,Lionel Apetoh,Fernando Aranda,Vincenzo Barnaba,Norma Bloy,Laura Bracci,Karine Breckpot,David Brough,Aitziber Buqué,Maria G. Castro,Mara Cirone,María Isabel Colombo,Isabelle Cremer,Sandra Demaria,Luciana Dini,Aristides G. Eliopoulos,Alberto Faggioni,Silvia C. Formenti,Jitka Fucikova,Lucia Gabriele,Udo S. Gaipl,Jérôme Galon,Abhishek D. Garg,François Ghiringhelli,Nathalia A. Giese,Zong Sheng Guo,Akseli Hemminki,Martin Herrmann,James W. Hodge,Stefan Holdenrieder,Jamie Honeychurch,Hong-Min Hu,Xing Huang,Timothy M Illidge,Koji Kono,Mladen Korbelik,Dmitri V. Krysko,Sherene Loi,Pedro R. Lowenstein,Enrico Lugli,Yuting Ma,Frank Madeo,Angelo A. Manfredi,Isabelle Martins,Domenico Mavilio,Laurie Menger,Nicolò Merendino,Michael Michaud,Grégoire Mignot,Karen L. Mossman,Gabriele Multhoff,Rudolf Oehler,Fabio Palombo,Theocharis Panaretakis,Jonathan Pol,Enrico Proietti,Jean-Ehrland Ricci,Chiara Riganti,Patrizia Rovere-Querini,Anna Rubartelli,Antonella Sistigu,Mark J. Smyth,Juergen Sonnemann,Radek Spisek,John Stagg,Abdul Qader Sukkurwala,Eric Tartour,Andrew Thorburn,Stephen H. Thorne,Peter Vandenabeele,Francesca Velotti,Samuel T Workenhe,Haining Yang,Wei-Xing Zong,Laurence Zitvogel,Guido Kroemer,Lorenzo Galluzzi +81 more
TL;DR: Strategies conceived to detect surrogate markers of ICD in vitro and to screen large chemical libraries for putative I CD inducers are outlined, based on a high-content, high-throughput platform that was recently developed.
782
DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells
Hiro Sato,Atsuko Niimi,Takaaki Yasuhara,Tiara Bunga Mayang Permata,Yoshihiko Hagiwara,Mayu Isono,Endang Nuryadi,Ryota Sekine,Takahiro Oike,Sangeeta Kakoti,Yuya Yoshimoto,Kathryn D. Held,Kathryn D. Held,Yoshiyuki Suzuki,Koji Kono,Kiyoshi Miyagawa,Takashi Nakano,Atsushi Shibata +17 more
TL;DR: The involvement of DSB repair in PD-L1 expression is revealed and mechanistic insight is provided into howPD-L 1 expression is regulated after DSBs, which requires ATM/ATR/Chk1 kinases and IRF1 signalling.
CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer.
Yoshiki Mizukami,Koji Kono,Yoshihiko Kawaguchi,Hidenori Akaike,Kazuyasu Kamimura,Hidemitsu Sugai,Hideki Fujii +6 more
TL;DR: CCL17 and CCL22 within the tumor are related to the increased population of Foxp3+ Tregs, with such an observation occurring in early gastric cancer.
380
EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus.
Mitsuhiko Hanawa,Shioto Suzuki,Yoh Dobashi,Tetsu Yamane,Koji Kono,Nobuyuki Enomoto,Akishi Ooi,Akishi Ooi +7 more
TL;DR: In conclusion, anti‐EGFR therapies may be appropriate for patients with ESCC and combined analyses by immunohistochemistry/FISH would clarify aberrations in protein and gene function, and could help to identify those patients who may benefit from anti-EGFR therapy.
322
A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
TL;DR: The development of an electroporation method that permits rapid expression of the receptor in a large number of human NK cells facilitates clinical translation of this NK-based strategy for a generalized cellular therapy that may be useful to treat a wide range of cancers.
312