Kinga Lis
University of Illinois at Chicago
31 Papers
36 Citations
Kinga Lis is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 8 publications. Previous affiliations of Kinga Lis include Veterans Health Administration.
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Papers
Multi-modal contributions to detoxification of acute pharmacotoxicity by a triglyceride micro-emulsion.
Michael R. Fettiplace,Kinga Lis,Richard Ripper,Katarzyna Kowal,Adrian Pichurko,Dominic Vitello,Israel Rubinstein,David E. Schwartz,Belinda S. Akpa,Guy L. Weinberg,Guy L. Weinberg +10 more
TL;DR: An integrated mechanism of reversal of bupivacaine toxicity that includes both transient drug scavenging and a cardiotonic effect that couple to accelerate movement of the toxin away from sites of toxicity is reported.
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The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures
Douglas L. Feinstein,Douglas L. Feinstein,Belinda S. Akpa,Manuela A.A. Ayee,Anne I. Boullerne,Anne I. Boullerne,David Braun,Sergey V. Brodsky,David Gidalevitz,Zane Hauck,Sergey Kalinin,Kathy Kowal,Ivan Kuzmenko,Kinga Lis,Natalia Marangoni,Michael W. Martynowycz,Michael W. Martynowycz,Israel Rubinstein,Richard B. van Breemen,Kyle Ware,Guy L. Weinberg,Guy L. Weinberg +21 more
TL;DR: Superwarfarins were developed following the emergence of warfarin resistance in rodents as discussed by the authors, and they have a longer half-life and stronger affinity to vitamin K epoxide reductase.
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Insulin Signaling in Bupivacaine-induced Cardiac Toxicity: Sensitization during Recovery and Potentiation by Lipid Emulsion.
Michael R. Fettiplace,Katarzyna Kowal,Richard Ripper,Richard Ripper,Alexandria N. Young,Alexandria N. Young,Kinga Lis,Kinga Lis,Israel Rubinstein,Marcelo G. Bonini,Richard D. Minshall,Guy L. Weinberg +11 more
TL;DR: Glucose handling by Akt and AMPK is integral to recovery from bupivacaine cardiotoxicity and modulation of these pathways by ILE contributes to lipid resuscitation.
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The Long-Lasting Rodenticide Brodifacoum Induces Neuropathology in Adult Male Rats.
Sergey Kalinin,Natalia Marangoni,Katarzyna Kowal,Arunangsu Dey,Kinga Lis,Sergey V. Brodsky,Richard B. van Breemen,Zane Hauck,Richard Ripper,Richard Ripper,Israel Rubinstein,Israel Rubinstein,Guy L. Weinberg,Guy L. Weinberg,Douglas L. Feinstein,Douglas L. Feinstein +15 more
TL;DR: It is demonstrated that superwarfarin accumulation increases indices of neuroinflammation and neuropathology in adult rodents, suggesting that methods which minimize BDF toxicity may not address delayed neurological sequelae.
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Cardiac depression induced by cocaine or cocaethylene is alleviated by lipid emulsion more effectively than by sulfobutylether-β-cyclodextrin.
Michael R. Fettiplace,Michael R. Fettiplace,Adrian Pichurko,Adrian Pichurko,Richard Ripper,Richard Ripper,Bocheng Lin,Bocheng Lin,Katarzyna Kowal,Katarzyna Kowal,Kinga Lis,Kinga Lis,David E. Schwartz,Douglas L. Feinstein,Douglas L. Feinstein,Israel Rubinstein,Israel Rubinstein,Guy L. Weinberg,Guy L. Weinberg +18 more
TL;DR: A commercially available lipid emulsion was able to delay progression of cocaine cardiac toxicity in vivo, and may contribute to reversal of acute cocaine and cocaethylene cardiotoxicity, and beneficial effects may involve mitochondrial lipid processing.
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