18 Papers
323 Citations
Kimberly White is an academic researcher from Johnson & Johnson Pharmaceutical Research and Development. The author has contributed to research in topics: Thrombin receptor & Indole test. The author has an hindex of 11, co-authored 18 publications. Previous affiliations of Kimberly White include Millennium Pharmaceuticals & Janssen Pharmaceutica.
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Papers
Discovery and optimization of a novel series of thrombin receptor (par-1) antagonists: potent, selective peptide mimetics based on indole and indazole templates.
Han-Cheng Zhang,Claudia K. Derian,Patricia Andrade-Gordon,Hoekstra William J,David F. McComsey,Kimberly White,Brenda L. Poulter,Michael F. Addo,Wai-man Cheung,Bruce P. Damiano,Donna Oksenberg,E. E. Reynolds,Anjali Pandey,Robert M. Scarborough,Bruce E. Maryanoff +14 more
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Patent
Substituted pyrrolines as kinase inhibitors
Han-Cheng Zhang,Bruce E. Maryanoff,Mccomsey David F,Kimberly White,Hong Ye,Leonard R. Hecker,Bruce R. Conway,Keith T. Demarest +7 more
- 04 Jun 2003
TL;DR: In this paper, substituted pyrroline compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase/dualkinase mediated disorder are presented.
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Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3.
Han-Cheng Zhang,Kimberly White,Hong Ye,David F. McComsey,Claudia K. Derian,Michael F. Addo,Patricia Andrade-Gordon,Annette J. Eckardt,Bruce R. Conway,Lori Westover,Jun Z. Xu,Richard Look,Keith T. Demarest,Stuart Emanuel,Bruce E. Maryanoff +14 more
TL;DR: In cell-based functional assays, several compounds effectively blocked interleukin-8 release induced by PKC-betaII and increased glycogen synthase activity by inhibiting GSK-3beta and compound 5a had high selectivity in a screening panel of 10 other protein kinases.
59
Patent
Macroheterocylic compounds useful as kinase inhibitors
Gee-Hong Kuo,Han-Cheng Zhang,Prouty Catherine P,Alan Deangelis,Peter J. Connolly,William V. Murray,Lan Shen,Bruce R. Conway,Keith T. Demarest,Chandra R. Shah,Bruce E. Maryanoff,Kimberly White +11 more
- 06 Dec 2001
TL;DR: In this paper, the authors describe macroheterocyclic compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds, and methods for treating or ameliorating a kinase/dualkinase mediated disorder.
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Efficient synthesis of 3-substituted 2-arylindoles via Suzuki coupling reactions on the solid phase
TL;DR: Aryl-3-alkylindoles were synthesized on solid phase via palladium-mediated heteroannulation of 1alkyl-2-(trimethylsilyl)acetylene with amide resin-bound o-iodoaniline as mentioned in this paper.
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