Kevin M. Wright
Harvard University
39 Papers
220 Citations
Kevin M. Wright is an academic researcher from Harvard University. The author has contributed to research in topics: Population & Biology. The author has an hindex of 20, co-authored 38 publications. Previous affiliations of Kevin M. Wright include Medical College of Wisconsin & Duke University.
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Papers
The strength and genetic basis of reproductive isolating barriers in flowering plants
David B. Lowry,Jennifer L. Modliszewski,Kevin M. Wright,Carrie A. Wu,John H. Willis,John H. Willis +5 more
TL;DR: A comprehensive analysis involving 19 pairs of plant taxa and reviewed contemporary knowledge of the genetic architecture of reproductive isolation and the relative role of chromosomal and genic factors in intrinsic postzygotic isolation found that prezyGotic isolation is approximately twice as strong as postzealous isolation, and that postmating barriers are approximately three times more asymmetrical in their action than premating barriers.
Mimulus is an emerging model system for the integration of ecological and genomic studies.
TL;DR: Some of the phenotypic and genetic diversity in the genus Mimulus are introduced and how direct genetic studies with Mimulus can address a wide spectrum of ecological and evolutionary questions are highlighted.
Meiotic Adaptation to Genome Duplication in Arabidopsis arenosa
Levi Yant,Jesse D. Hollister,Kevin M. Wright,Brian J. Arnold,James D. Higgins,F. Chris H. Franklin,Kirsten Bomblies +6 more
TL;DR: This work investigates genome-wide patterns of differentiation between natural diploids and tetraploids of Arabidopsis arenosa, an outcrossing relative of A. thaliana, and indicates that even conserved meiotic processes can be capable of nimble evolutionary shifts when required.
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Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing
Uffe Hellsten,Kevin M. Wright,Jerry Jenkins,Shengqiang Shu,Yao-Wu Yuan,Susan R. Wessler,Jeremy Schmutz,John H. Willis,Daniel S. Rokhsar,Daniel S. Rokhsar +9 more
TL;DR: The general pattern is similar to that observed in yeast, as well as in positive-regulatory domain zinc finger protein 9–knockout mice, suggesting that recombination initiation described here in Mimulus may reflect ancient and conserved eukaryotic mechanisms.
Estimates of the Heritability of Human Longevity Are Substantially Inflated due to Assortative Mating
J. Graham Ruby,Kevin M. Wright,Kristin A. Rand,Amir R. Kermany,Keith Noto,Don Curtis,Neal Varner,Daniel Garrigan,Dmitri Slinkov,Ilya Dorfman,Julie M. Granka,Jake K. Byrnes,Natalie M. Myres,Catherine A. Ball +13 more
TL;DR: It is concluded that the true heritability of human longevity for birth cohorts across the 1800s and early 1900s was well below 10%, and that it has been generally overestimated due to the effect of assortative mating.
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