Kevin M. Shakesheff
University of Nottingham
307 Papers
2.7K Citations
Kevin M. Shakesheff is an academic researcher from University of Nottingham. The author has contributed to research in topics: Tissue engineering & PLGA. The author has an hindex of 72, co-authored 301 publications. Previous affiliations of Kevin M. Shakesheff include Massachusetts Institute of Technology & National University of Ireland, Galway.
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Papers
Drug delivery to the ear
E Hoskison,Matija Daniel,Matija Daniel,Saif Al-Zahid,Saif Al-Zahid,Kevin M. Shakesheff,Roger Bayston,JP Birchall +7 more
TL;DR: There are numerous methods of drug delivery to the middle ear, which can be categorized as topical, systemic (intravenous), transtympanic and via the Eustachian tube.
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In situ Atomic Force Microscopy Imaging of Polymer Degradation in an Aqueous Environment
Kevin M. Shakesheff,M. C. Davies,Clive J. Roberts,S. J. B. Tendler,Alexander G. Shard,Abraham J. Domb +5 more
TL;DR: In this paper, an atomic force microscopy (AFM) was employed for the in situ study of the hydrolytic surface erosion of biodegradable polymers within an aqueous environment.
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Direct calculation of Maxwell stress tensor for accurate trajectory prediction during DEP for 2D and 3D structures
Ahmed Al-Jarro,John Paul,David Thomas,John A. Crowe,N Sawyer,Felicity R. A. J. Rose,Kevin M. Shakesheff +6 more
TL;DR: In this article, a robust numerical tool based on calculation of the Maxwell stress tensor (MST) both in a 2D and in a 3D formulation was developed to provide a deeper understanding of cells interaction using DEP as a handle to position and manipulate cells for fundamental cell biology.
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Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry.
Francesca Intranuovo,Daniel Howard,Lisa J. White,Ramneek K. Johal,Amir M. Ghaemmaghami,Pietro Favia,Steven M. Howdle,Kevin M. Shakesheff,Morgan R. Alexander +8 more
TL;DR: A vapour phase coating strategy which is readily applicable to any porous solid to provide a uniform cellular distribution is developed and encourages 3T3 fibroblast cells to adhere homogeneously from the periphery to the centre, when balanced by the tortuousity of the pore structure.
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Patent
Porous matrix comprising cross-linked particles
Kevin M. Shakesheff,Aliasger K. Salem +1 more
- 21 Jun 2002
TL;DR: An open porous matrix of particulate material for in vivo use in or on a target tissue in medicine, the matrix comprising particles cross-linked with one another so as to define pores there between and uses therefor are described as discussed by the authors.
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