Kevin M. Shakesheff
University of Nottingham
307 Papers
2.7K Citations
Kevin M. Shakesheff is an academic researcher from University of Nottingham. The author has contributed to research in topics: Tissue engineering & PLGA. The author has an hindex of 72, co-authored 301 publications. Previous affiliations of Kevin M. Shakesheff include Massachusetts Institute of Technology & National University of Ireland, Galway.
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Papers
Chemical and Morphological Analysis of Surface Enrichment in a Biodegradable Polymer Blend by Phase-Detection Imaging Atomic Force Microscopy
Xinyong Chen,Simon L. McGurk,Martyn C. Davies,Clive J. Roberts,Kevin M. Shakesheff,S. J. B. Tendler,Philip M. Williams,John K. Davies,Dawkes Adrian Charles,Abraham J. Domb +9 more
TL;DR: In this article, the surface enrichment of components from a biodegradable polymer blend composed of poly(sebacic anhydride) (PSA) and poly(dl-lactic acid) (PLA) is analyzed using atomic force microscopy (AFM).
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Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester
Chiara Gualandi,Lisa J. White,Liu Chen,Richard A. Gross,Kevin M. Shakesheff,Steven M. Howdle,Mariastella Scandola +6 more
TL;DR: A preliminary study of the mechanical properties of the scaffolds revealed that poly(PDL-CL) foams may find application in the regeneration of cartilage tissue.
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Putting the fizz into chemistry: applications of supercritical carbon dioxide in tissue engineering, drug delivery and synthesis of novel block copolymers
TL;DR: The recent progress at Nottingham towards the exploitation of the unique properties of scCO(2) (supercritical carbon dioxide) for the preparation of polymeric scaffolds for tissue engineering applications and new devices for controlled drug delivery is described.
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Patent
Surface coating in spatially controlled patterns
Kevin M. Shakesheff,Nikin Patel,Scott M. Cannizzaro,Robert Langer +3 more
- 20 Jan 1999
TL;DR: In this paper, a biodegradable and biocompatible polymer article having a surface where a biologically active ligand is provided on said surface in a spatially controlled pattern is presented.
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Controlling Biological Interactions with Poly(lactic acid) by Surface Entrapment Modification
TL;DR: It is demonstrated by high-resolution X-ray photoelectron spectroscopy that control over the PEG surface density may be achieved by using predetermined process conditions, such as a particular solvent/nonsolvent ratio or a set polymer treatment time, and that surface coverage of around 75% is possible.
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