Kevin J. Tracey
The Feinstein Institute for Medical Research
609 Papers
4.5K Citations
Kevin J. Tracey is an academic researcher from The Feinstein Institute for Medical Research. The author has contributed to research in topics: Inflammation & Medicine. The author has an hindex of 138, co-authored 561 publications. Previous affiliations of Kevin J. Tracey include Memorial Sloan Kettering Cancer Center & Hofstra University.
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Papers
Regulation of Posttranslational Modifications of HMGB1 During Immune Responses.
Yiting Tang,Xin Zhao,Daniel J. Antoine,Xianzhong Xiao,Haichao Wang,Ulf Andersson,Timothy R. Billiar,Kevin J. Tracey,Ben Lu +8 more
TL;DR: The full picture and the detailed molecular mechanisms of how cells regulate the posttranslational modifications and the redox status of HMGB1 during immune responses or under stress not only unravel the molecular mechanisms by which cells regulates the release and the biological function of HMTB but may also provide novel therapeutic targets to treat inflammatory diseases.
HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice
Penny L. Sappington,Runkuan Yang,Huan Yang,Kevin J. Tracey,Russell L. Delude,Mitchell P. Fink +5 more
TL;DR: The view that HMGB1 and B box are capable of causing alterations in gut barrier function via a mechanism that depends on the formation of NO and ONOO(-) is supported.
Exploring the vagus nerve and the inflammatory reflex for therapeutic benefit in chronic spinal cord injury
TL;DR: Exploring the potential of the vagus nerve-based inflammatory reflex to restore autonomic regulation and control inflammation may provide a novel approach for functional improvement in SCI.
Is severe sepsis a neuroendocrine disease
TL;DR: How these networks normally cooperate to enhance antimicrobial host defense and regulate local inflammation are reviewed and the possibility that CNS dysfunction contributes to the pathogenesis of severe sepsis is discussed.
Exercise-mediated peripheral tissue and whole-body amino acid metabolism during intravenous feeding in normal man.
J. D. Albert,J. D. Albert,Dwight E. Matthews,Dwight E. Matthews,Adrian Legaspi,Adrian Legaspi,Kevin J. Tracey,Kevin J. Tracey,Malayappa Jeevanandam,Malayappa Jeevanandam,Murray F. Brennan,Murray F. Brennan,Stephen F. Lowry,Stephen F. Lowry +13 more
TL;DR: The effect of a daily submaximal exercise regimen on whole-body and peripheral tissue amino acid metabolism during weight-stable intravenous feeding (IVF) was evaluated in 11 normal volunteers.