Kerstin Zwirner
University of Tübingen
13 Papers
31 Citations
Kerstin Zwirner is an academic researcher from University of Tübingen. The author has contributed to research in topics: Medicine & Magnetic resonance imaging. The author has an hindex of 9, co-authored 13 publications.
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Papers
Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors
Franziska Eckert,Franziska Eckert,Kerstin Zwirner,S. Boeke,S. Boeke,Daniela Thorwarth,Daniela Thorwarth,Daniel Zips,Daniel Zips,Stephan M. Huber +9 more
TL;DR: It is hypothesized that the subgroup of patients with hypoxic tumors might be of special interest for combining immune checkpoint inhibition with radiotherapy, due to local therapy resistance but also increased rate of distant metastases and the strong immune suppression induced by hypoxia.
Neutrophil-to-Lymphocyte Ratio in Rectal Cancer-Novel Biomarker of Tumor Immunogenicity During Radiotherapy or Confounding Variable?
LH Braun,David Baumann,Kerstin Zwirner,Ewald Eipper,Franziska Hauth,Andreas Peter,Daniel Zips,Daniel Zips,Cihan Gani,Cihan Gani +9 more
TL;DR: An elevated pretherapeutic NLR was associated with higher T stage, inferior DFS, and poor pathological response to neoadjuvant radiochemotherapy, and a strong correlation between NLR and primary tumor volume was seen.
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Radiation Pneumonitis after Intensity-Modulated Radiotherapy for Esophageal Cancer: Institutional Data and a Systematic Review.
J J Tonison,Stefan Georg Fischer,Marén Viehrig,Stefan Welz,S. Boeke,S. Boeke,Kerstin Zwirner,B. Klumpp,LH Braun,Daniel Zips,Daniel Zips,Cihan Gani +11 more
TL;DR: Investigation of the incidence of RP after radiochemotherapy with intensity modulated radiotherapy (IMRT) in patients with esophageal cancer and correlate this with dose volume histogram (DVH) related parameters shows a low incidence, however, efforts should be made to keep the lung V20 below 23% and specific caution is warranted in Patients with pre-existing lung conditions.
Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D
Kerstin Zwirner,Franz J. Hilke,German Demidov,Jairo Socarras Fernandez,Stephan Ossowski,Cihan Gani,Cihan Gani,Daniela Thorwarth,Daniela Thorwarth,Olaf Riess,Daniel Zips,Daniel Zips,Christopher Schroeder,Stefan Welz,Stefan Welz +14 more
TL;DR: An association of somatic mutations in FAT1 with reduced radiomic tumour heterogeneity could potentially elucidate the previously described favourable outcomes of these patients, and further studies are needed to validate this exploratory data in the future.
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Assessment of image quality of a radiotherapy-specific hardware solution for PET/MRI in head and neck cancer patients
R. Winter,Sara Leibfarth,Holger Schmidt,Kerstin Zwirner,David Mönnich,Stefan Welz,Nina F. Schwenzer,Christian la Fougère,Konstantin Nikolaou,Sergios Gatidis,Daniel Zips,Daniela Thorwarth +11 more
TL;DR: Though SNR was reduced, the image quality obtained with a radiotherapy setup meets RTP requirements and the data can thus be used for personalized RTP.
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