Kerry E. Travers
Beth Israel Deaconess Medical Center
5 Papers
56 Citations
Kerry E. Travers is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Heart failure & Skeletal muscle. The author has an hindex of 5, co-authored 5 publications.
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Papers
Cardiovascular Abnormalities in Transgenic Mice With Reduced Brown Fat An Animal Model of Human Obesity
Antonio Cittadini,Christos S. Mantzoros,Thomas G. Hampton,Kerry E. Travers,Sarah E. Katz,James P. Morgan,Jeffrey S. Flier,Pamela S. Douglas +7 more
TL;DR: Transgenic ablation of brown adipose tissue is associated not only with obesity but also with systemic hypertension, left ventricular hypertrophy with eccentric remodeling and fibrosis, and high cardiac output, a unique constellation of findings strikingly similar to that seen in human obesity.
63
Intracellular calcium dynamics in mouse model of myocardial stunning
TL;DR: Simultaneous assessment of intracellular calcium and left ventricular function demonstrates that calmodulin-regulated mechanisms may contribute to the pathogenesis of myocardial stunning in the mouse heart and indicates correlation of interventions that regulate Ca2+ exchange with functional alterations.
49
Deficient cellular cyclic AMP may causeboth cardiac and skeletal muscle dysfunction in heart failure
Jessica D. Grossman,Amy Bishop,Kerry E. Travers,Cynthia Perreault,John H. Woolf,Thomas G. Hampton,Hector Rasgado-Flores,Hugo Gonzalez-Serratos,James P. Morgan +8 more
TL;DR: EDL skeletal muscle from rats with CHF had intrinsic abnormalities in excitation-contraction coupling that could be reversed with cyclic AMP supplementation as previously reported for the heart, suggesting that deficient AMP levels may contribute to both cardiac and skeletal muscle dysfunction in CHF.
6
Alterations in heart failure of cyclic AMP-dependent inotropic and lusitropic properties of cardiac and skeletal muscle.
Amy Bishop,Kerry E. Travers,Jessica D. Grossman,Heather Johnson,Cynthia Perreault,John H. Woolf,Antonio Cittadini,Hugo Gonzales-Serratos,Hugo Gonzales-Serratos,James P. Morgan +9 more
TL;DR: Results suggest that therapy aimed at restoring cyclic AMP to normal levels may be effective with regard to improving systolic and diastolic function in the heart and may decrease the development of fatigue in skeletal muscle of patients with failure.
5
Abnormal cardiac function in the streptozotocin-induced, non–insulin-dependent diabetic rat: Noninvasive assessment with Doppler echocardiography and contribution of the nitric oxide pathway
Ian I Joffe,Kerry E. Travers,Cynthia L. Perreault-Micale,Thomas G. Hampton,Sarah E. Katz,James P. Morgan,Pamela S. Douglas +6 more
TL;DR: Diabetic cardiomyopathy is characterized by LV systolic and diastolic dysfunction, the latter correlating with decreased exhaled NO, and the NO pathway is intact, suggesting impaired availability of NO as contributor to cardiomeopathy.