Kensuke Asaba
University of Tokyo
17 Papers
110 Citations
Kensuke Asaba is an academic researcher from University of Tokyo. The author has contributed to research in topics: Odds ratio & Mendelian randomization. The author has an hindex of 8, co-authored 15 publications.
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Papers
Effects of NADPH oxidase inhibitor in diabetic nephropathy
Kensuke Asaba,Akihiro Tojo,Akihiro Tojo,Akihiro Tojo,Maristela L. Onozato,Maristela L. Onozato,Maristela L. Onozato,Atsuo Goto,Atsuo Goto,Atsuo Goto,Mark T. Quinn,Mark T. Quinn,Mark T. Quinn,Toshiro Fujita,Toshiro Fujita,Toshiro Fujita,Christopher S. Wilcox,Christopher S. Wilcox,Christopher S. Wilcox +18 more
TL;DR: Activation of NADPH oxidase with translocation of p47phox to the membrane underlies the oxidative stress and limited NO generation, despite enhanced eNOS expression in a model of diabetic nephropathy.
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Double-edged action of SOD mimetic in diabetic nephropathy.
TL;DR: In conclusion, tempol inhibited glomerular matrix expansion via suppression of peroxide production and TGF-β, but it failed to reduce proteinuria, probably due to the increased hypochlorite production in diabetic nephropathy.
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Detection of myeloperoxidase in membranous nephropathy-like deposits in patients with anti-neutrophil cytoplasmic antibody–associated glomerulonephritis
Kikuno Hanamura,Akihiro Tojo,Satoshi Kinugasa,Kensuke Asaba,Maristela L. Onozato,Hiroshi Uozaki,Masashi Fukayama,Toshiro Fujita +7 more
TL;DR: The glomerular localization of myeloperoxidase was examined by double immunofluorescence and immunoelectron microscopy in cases of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis with membranous nephropathy-like immunoglobulin G deposition to investigate the immune complex antigens in these cases.
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Long-term renal prognosis of IgA nephropathy with therapeutic trend shifts.
Kensuke Asaba,Akihiro Tojo,Maristela L. Onozato,Satoshi Kinugasa,Hiroki Miyazaki,Kazuhisa Miyashita,Yoshio Uehara,Yasunobu Hirata,Kenjiro Kimura,Atsuo Goto,Masao Omata,Toshiro Fujita +11 more
TL;DR: Treatment with renin-angiotensin system inhibitors showed the greatest improvement of 20-year renal survival in IgA nephropathy patients.
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Nitric oxide generated by nNOS in the macula densa regulates the afferent arteriolar diameter in rat kidney.
Akihiro Tojo,Maristela L. Onozato,Satoru Fukuda,Kensuke Asaba,Kenjiro Kimura,Toshiro Fujita +5 more
- 01 Dec 2004
TL;DR: The afferent arteriolar diameter might be regulated by NO derived from nNOS in the macula densa in DOCA-salt hypertensive rats.
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