Kenshiro Matsuda
Tokyo University of Agriculture and Technology
18 Papers
21 Citations
Kenshiro Matsuda is an academic researcher from Tokyo University of Agriculture and Technology. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 7, co-authored 15 publications. Previous affiliations of Kenshiro Matsuda include University of Tsukuba.
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Papers
Skin pH Is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model
Hyosun Jang,Akira Matsuda,Kyungsook Jung,Kaoru Karasawa,Kenshiro Matsuda,Kumiko Oida,Saori Ishizaka,Ginnae Ahn,Yosuke Amagai,Changjong Moon,Sung-Ho Kim,Peter D. Arkwright,Kenji Takamori,Hiroshi Matsuda,Akane Tanaka +14 more
TL;DR: Alkalinization of the skin of asymptomatic NC/Tnd mice housed in specific pathogen-free (SPF) conditions induced KLK5 and activated the protease-activated receptor 2 (PAR2), resulting in thymic stromal lymphopoietin (TSLP) secretion and a cutaneous T-helper 2 allergic response.
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Staphylococcus aureus Second Immunoglobulin-Binding Protein drives atopic dermatitis via IL-33
Arwa Al Kindi,Helen L. Williams,Kenshiro Matsuda,Abdullah M. Alkahtani,Charis R Saville,Hayley M. Bennett,Yasmine Alshammari,Soo Yee Tan,Catherine A. O'Neill,Akane Tanaka,Hiroshi Matsuda,Peter D. Arkwright,Joanne L. Pennock +12 more
TL;DR: It is shown that IL-33 was essential in inducing the immune response to S. aureus in vivo, and the Second Immunoglobulin-Binding Protein (Sbi) is a unique type 2-promoting virulence factor capable of initiating the type-2 promoting cytokine activity underlying AD.
Dihomo-γ-linolenic acid prevents the development of atopic dermatitis through prostaglandin D1 production in NC/Tnd mice.
Yosuke Amagai,Kumiko Oida,Akira Matsuda,Kyungsook Jung,Saki Kakutani,Takao Tanaka,Kenshiro Matsuda,Hyosun Jang,Ginae Ahn,Yan Xia,Hiroshi Kawashima,Hiroshi Shibata,Hiroshi Matsuda,Akane Tanaka +13 more
TL;DR: Oral administration of DGLA causes preventive effects on AD development in NC/Tnd mice by regulating the PGD1 supply, and quantifying the 20-carbon fatty acid-derived eicosanoids in the skin found to upregulate PGD 1, which correlated with a better outcome inNC/T second mice.
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Dieckol, a phlorotannin of Ecklonia cava, suppresses IgE-mediated mast cell activation and passive cutaneous anaphylactic reaction.
Ginnae Ahn,Ginnae Ahn,Yosuke Amagai,Akira Matsuda,Sung-Myung Kang,WonWoo Lee,Kyungsook Jung,Kumiko Oida,Hyosun Jang,Saori Ishizaka,Kenshiro Matsuda,You-Jin Jeon,Youngheun Jee,Hiroshi Matsuda,Akane Tanaka +14 more
TL;DR: Keywords: Dieckol; Ecklonia cava ; mast cell; passive cutaneous anaphylactic reaction; passive Cutaneous Anaphylaxis reaction.
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Amelioration of atopic-like skin conditions in NC/Tnd mice by topical application with distilled Alpinia intermedia Gagnep extracts.
Yosuke Amagai,Yosuke Amagai,Chihiro Katsuta,Yoshihiro Nomura,Kumiko Oida,Kenshiro Matsuda,Hyosun Jang,Ginnae Ahn,Tetsuyoshi Hamasaki,Hiroshi Matsuda,Akane Tanaka +10 more
TL;DR: Topical application with the A. intermedia extract to the skin of NC/Tnd mice improved the condition of the skin by suppressing multiple inflammatory responses, indicating that the extracts may become novel skin‐care remedies for AD patients.
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