Kenneth Day
University of Washington
28 Papers
225 Citations
Kenneth Day is an academic researcher from University of Washington. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 16, co-authored 26 publications. Previous affiliations of Kenneth Day include University of Texas Health Science Center at San Antonio.
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Papers
Nestin-GFP reporter expression defines the quiescent state of skeletal muscle satellite cells.
TL;DR: The NES-GFP model reveals unique transcriptional activity within quiescent satellite cells and permits novel insight into the heterogeneity of their molecular signatures and reflects the cycle of satellite cell self-renewal.
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The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny.
TL;DR: A reduction in satellite cells per myofiber with age is demonstrated that is more prominent in females compared to males and could be attributed to a reduced capacity to generate a reserve population.
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Defining the transcriptional signature of skeletal muscle stem cells.
TL;DR: Recent studies using transgenic mice in which satellite cells are traced and isolated based on their expression of green fluorescence protein driven by regulatory elements of the nestin promoter provide a novel means of studying satellite cell transcriptional signatures, heterogeneity among muscle groups, and the role of the myogenic niche in directing satellite cell self-renewal.
Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages
MacLean Sellars,Jun R. Huh,Kenneth Day,Priya D. Issuree,Carolina Galan,Stéphane Gobeil,Devin Absher,Michael R. Green,Dan R. Littman +8 more
TL;DR: It is suggested that stage-specific methylation and demethylation events in Cd4 regulate its heritable expression in response to the distinct signals that dictate lineage 'choice' during T cell development.
Comprehensive analysis of blood coagulation pathways in teleostei: evolution of coagulation factor genes and identification of zebrafish factor VIIi.
TL;DR: It is found that zebrafish carry all hemostatic genes present in mammals, providing evidence that the coagulation system of teleosts is nearly identical to mammals.
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