Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
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Papers
The Incidence and Associated Factors of Early Neurological Deterioration After Thrombolysis: Results From SITS Registry
Wai M. Yu,Azmil H. Abdul-Rahim,Alan C. Cameron,Janika Kõrv,Petr Sevcik,Danilo Toni,Kennedy R. Lees +6 more
TL;DR: The routinely observed rate of END reflected by real-world data is low, but END greatly increases risk of disability and mortality, and readily identifiable factors predict END may help with understanding causal mechanisms to assist prevention of END.
Methods to improve patient recruitment and retention in stroke trials
Eivind Berge,Christian Stapf,Rustam Al-Shahi Salman,Gary A. Ford,Peter Sandercock,H. Bart van der Worp,Jesper Petersson,Diederik W.J. Dippel,Derk W. Krieger,Kennedy R. Lees +9 more
TL;DR: A survey and workshop among 56 European stroke trialists was conducted to identify barriers, suggest methods to improve recruitment and retention, and make a priority list of interventions that merit further evaluation.
Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis.
Lars Kellert,Christian Hametner,Niaz Ahmed,Geraldine Rauch,Mary Joan MacLeod,Francesco Perini,Kennedy R. Lees,Peter A. Ringleb +7 more
TL;DR: The need for a more individual BP management accounting for pre-treatment BP and the acute BP course (ie, BPV) to achieve best possible outcome for the patient is suggested.
Derivation and Validation of a Modified Short Form of the Stroke Impact Scale
Rachael L. MacIsaac,Myzoon Ali,Michele Peters,Coralie English,Helen Rodgers,Crispin Jenkinson,Kennedy R. Lees,Terence J. Quinn +7 more
TL;DR: Using multiple, complementary methods, an SF‐SIS is derived and demonstrated content, convergent, and discriminant validity and this shortened SIS should allow collection of robust quality of life data with less associated test burden.
Comparison of stratification and adaptive methods for treatment allocation in an acute stroke clinical trial
TL;DR: The feasibility of adaptive stratification in the context of a clinical trial of insulin to control plasma glucose level following acute stroke and the importance of the method of analysis in realizing the gain in power which may potentially be achieved by allocating treatments using stratified random blocks or adaptive stratisation is considered.