Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
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Papers
Effect of Perindopril on Cerebral Vasomotor Reactivity in Patients With Lacunar Infarction
TL;DR: Evidence of a significant improvement in cerebral vasomotor reactivity induced by perindopril is provided, beyond any effect on blood pressure, and a role for the renin-angiotensin axis in the pathophysiology of subcortical small vessel disease is suggested.
Effect of Hyperthermia on Prognosis After Acute Ischemic Stroke
TL;DR: Gender, stroke severity, white blood cell count, and antibiotic use were significantly associated with hyperthermia, which is associated with a poor clinical outcome in patients with acute ischemic stroke.
The Virtual International Stroke Trials Archive (VISTA): results and impact on future stroke trials and management of stroke patients
Christian Weimar,Myzoon Ali,Kennedy R. Lees,Erich Bluhmki,Geoffrey A. Donnan,Hans-Christoph Diener +5 more
TL;DR: The Virtual International Stroke Trials Archive provides an excellent opportunity for analysis of natural history data and prognosis and has the potential to influence clinical trial design and implementation through exploratory data analyses.
Clinical Experience With Excitatory Amino Acid Antagonist Drugs
Keith W. Muir,Kennedy R. Lees +1 more
TL;DR: Antagonists of the N-methyl-D-aspartate (NMDA) receptor are furthest advanced in clinical development for stroke, and a similar pattern of side effects is apparent with the majority of agents, however, cardiovascular effects may ultimately define therapeutic index for each drug.
Thrombolysis outcomes in acute ischemic stroke patients with prior stroke and diabetes mellitus.
Nishant K. Mishra,Niaz Ahmed,Antonio Dávalos,Helle K. Iversen,Teresa Pinho e Melo,Lauri Soinne,N Wahlgren,Kennedy R. Lees +7 more
TL;DR: Outcomes from thrombolysis are better than the controls among patients with DM, PS, or both, and there is no statistical justification for the exclusion of patients with concomitant diabetes mellitus and prior stroke from receiving thROMbolytic therapy.