Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
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Papers
PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment:
Hendrik Reinink,Jeroen C. de Jonge,Philip M.W. Bath,Diederik van de Beek,Eivind Berge,Saskia Borregaard,Alfonso Ciccone,László Csiba,Jacques Demotes,Diederik W.J. Dippel,Janika Kõrv,Iwona Kurkowska-Jastrzębska,Kennedy R. Lees,Malcolm R. Macleod,George Ntaios,Gary Randall,Götz Thomalla,H. Bart van der Worp +17 more
- 30 Apr 2018
TL;DR: This trial will provide evidence for a simple, safe and generally available treatment strategy that may reduce the burden of death or disability in patients with stroke at very low costs.
Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial [ISRCTN19943732]
Andrew Bradford,Kennedy R. Lees +1 more
TL;DR: The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council and when complete, it will be the largest single neuroprotective study undertaken to date.
Associations between meteorological variables and acute stroke hospital admissions in the west of Scotland
Jesse Dawson,Christopher J. Weir,Fiona Wright,C. Bryden,Stella Aslanyan,Kennedy R. Lees,William Bird,Matthew Walters +7 more
TL;DR: A large clinical stroke registry with the UK Met Office database was combined to assess the association between meteorological variables and specific clinical subtypes of acute stroke.
Blood-brain barrier leakage increases with small vessel disease in acute ischemic stroke.
TL;DR: The results support that SVD score has construct validity, and confirm a relation between SVD and BBB disruption also in patients with acute stroke, which is associated with increased BBB leakage in both acutely ischemic and nonischemic area.
Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis
William Whiteley,Jonathan Emberson,Kennedy R. Lees,Lisa Blackwell,Gregory W. Albers,Erich Bluhmki,Thomas G. Brott,Geoff Cohen,Stephen M. Davis,Geoffrey A. Donnan,James C. Grotta,George Howard,Markku Kaste,Masatoshi Koga,Rüdiger von Kummer,Maarten G Lansberg,Richard I. Lindley,Patrick D. Lyden,Jean-Marc Olivot,Mark W Parsons,Danilo Toni,Kazunori Toyoda,Nils Wahlgren,Joanna M. Wardlaw,Gregory J. del Zoppo,Peter Sandercock,Werner Hacke,Colin Baigent +27 more
TL;DR: The proportional and absolute effects of alteplase on the risks of intracerebral haemorrhage, mortality, and functional impairment in different types of patients were determined.