Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
Chat about Author
Papers
Tolerability of NXY-059 at higher target concentrations in patients with acute stroke.
TL;DR: NXY-059 was well tolerated in patients with an acute stroke at and above concentrations shown to be neuroprotective in an animal model when initiated 4 hours after onset of permanent focal ischemia.
Quantification of ultrasound emboli signals in patients with cardiac and carotid disease.
TL;DR: There is promise of being able to distinguish emboli on the basis of power measurements, and emboli of different sources appear to have different ultrasonic characteristics, which are likely to be based on composition and size.
Tolerability of the Low-Affinity, Use-Dependent NMDA Antagonist AR-R15896AR in Stroke Patients A Dose-Ranging Study
TL;DR: The maximum tolerated loading infusion of AR-R15896AR in this study was 250 mg over a period of 1 hour, and putative neuroprotective concentrations of 1240 ng/mL are attained by the loading dose and are satisfactorily maintained thereafter.
National Institutes of Health Stroke Scale Item Profiles as Predictor of Patient Outcome External Validation on Independent Trial Data
Azmil H. Abdul-Rahim,Rachael L. Fulton,Heidi Sucharew,Dawn Kleindorfer,Pooja Khatri,Joseph P. Broderick,Kennedy R. Lees,Andrei V. Alexandrov,Philip M.W. Bath,Erich Bluhmki,N. M. Bornstein,L. Claesson,J. Curram,Stephen M. Davis,Geoffrey A. Donnan,H. C. Diener,Marc Fisher,Myron D. Ginsberg,Barbara A. Gregson,James C. Grotta,Werner Hacke,M.G. Hennerici,Marc Hommel,Markku Kaste,P. Lyden,John R. Marler,K. W. Muir,Ralph L. Sacco,A. Shuaib,P. Teal,N Wahlgren,Steven Warach,C. Weimar +32 more
TL;DR: In this article, an independent latent class analysis was applied to derive secondary symptom grouping, b -NIHSS item profiles. But, the analysis was performed in an acute cohort.
Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial
Graeme J. Hankey,John W. Eikelboom,Qilong Yi,Kennedy R. Lees,Christopher Chen,Denis Xavier,Jose C. Navarro,Udaya K. Ranawaka,Wasim Uddin,Stefano Ricci,John Gommans,Reinhold Schmidt +11 more
TL;DR: The hypothesis that antiplatelet therapy modifies the potential benefits of lowering homocysteine with B-vitamin supplementation in the secondary prevention of major vascular events is supported.