Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
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Papers
Intravenous thrombolysis for acute ischaemic stroke: Preliminary experience with recombinant tissue plasminogen activator in the UK
TL;DR: The preliminary experience of implementing intravenous thrombolytic therapy for acute ischaemic stroke in three UK stroke centres is presented and patients treated were more severely affected than in other published European and North American series.
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A randomized 500-subject open-label phase 3 clinical trial of minimally invasive surgery plus alteplase in intracerebral hemorrhage evacuation (MISTIE III)
Wendy C. Ziai,Nichol McBee,Karen Lane,Kennedy R. Lees,Jesse Dawson,Paul M. Vespa,Richard E. Thompson,A. David Mendelow,Carlos S. Kase,J. Ricardo Carhuapoma,Carol B. Thompson,Steven Mayo,Pat Reilly,Scott Janis,Craig S. Anderson,Mark R. Harrigan,Paul J. Camarata,Jean-Louis Caron,Mario Zuccarello,Issam A. Awad,Daniel F Hanley,Mistie Iii Investigators +21 more
TL;DR: MISTIE III is an investigator-initiated multicenter, randomized, open-label phase 3 study investigating whether minimally invasive clot evacuation with thrombolysis improves functional outcomes at 365 days compared to conservative management.
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Management of acute stroke.
TL;DR: Stroke management requires attention to simple details and has been summarised in clinical guidelines and neuroprotection remains experimental, though magnesium is potentially of interest.
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The dose-response relationship with angiotensin converting enzyme inhibitors: effects on blood pressure and biochemical parameters.
TL;DR: Plasma angiotensin converting enzyme (ACE) inhibition and doseresponse relationships during blood pressure reductions were compared for several marketed ACE inhibitor compounds to clarify the dose-response relationship.
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•Journal Article
Abstract 15462: Risk of Stroke in Chronic Heart Failure Patients without Atrial Fibrillation: Analysis of the CORONA and GISSI-HF Trials
Azmil H. Abdul-Rahim,Rachael L. Fulton,Ana Cristina Perez,Luigi Tavazzi,Aldo P. Maggioni,Kennedy R. Lees,John J.V. McMurray +6 more
TL;DR: In a large contemporary HF population, it is found that a third of patients without AF have a risk of stroke that is at least as great as in HF patients with AF and a clinical trial of prophylactic anticoagulation is merited in these patients.
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