Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
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Papers
Apolipoprotein E genotype, coagulation, and survival following acute stroke.
Christopher J. Weir,Mark O. McCarron,Keith W. Muir,A. G. Dyker,Ian Bone,Kennedy R. Lees,James A. R. Nicoll +6 more
TL;DR: Among 529 ischemic stroke patients, increasing ε4 allele dose was associated with improved survival, and relative anticoagulation does not fully explain the survival advantage in ε 4-carrying ischeMIC stroke patients.
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Differing early blood pressure and renin-angiotensin system responses to the first dose of angiotensin-converting enzyme inhibitors in congestive heart failure
TL;DR: The disparate blood pressure responses to perindopril and enalapril in CHF are confirmed and there is no evidence of slow, tight binding or steric hindrance to explain these differences.
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Cluster-randomized, controlled trial of computer-based decision support for selecting long-term anti-thrombotic therapy after acute ischaemic stroke.
Christopher J. Weir,Kennedy R. Lees,Ronald S. MacWalter,Keith W. Muir,Wallesch Cw,McLelland Ev,Hendry A +6 more
TL;DR: A computer-based decision support system (CDSS) that provided patient-specific estimates of the expected ischaemic and haemorrhagic vascular event rates under each potential anti-thrombotic therapy was feasible to implement and acceptable to clinicians, but did not substantially influence prescribing practice.
Glyceryl Trinitrate for Acute Intracerebral Hemorrhage: Results From the Efficacy of Nitric Oxide in Stroke (ENOS) Trial, a Subgroup Analysis
Kailash Krishnan,Polly Scutt,Lisa J Woodhouse,Alessandro Adami,Jennifer L. Becker,Eivind Berge,Lesley Cala,Ana M. Casado,Valeria Caso,Christopher Chen,Hanna Christensen,Ronan Collins,Anna Członkowska,Robert A. Dineen,John Gommans,Panos Koumellis,Panos Koumellis,Panos Koumellis,Kennedy R. Lees,George Ntaios,Şerefnur Öztürk,Şerefnur Öztürk,Şerefnur Öztürk,Stephen J. Phillips,Stuart J. Pocock,Asita de Silva,Nikola Sprigg,Szabolcs Szatmári,Joanna M. Wardlaw,Philip M.W. Bath +29 more
TL;DR: In patients with intracerebral hemorrhage within 48 hours of onset, GTN lowered blood pressure was safe but did not improve functional outcome, and very early treatment might be beneficial but needs assessment in further studies.
A pilot study of streptokinase for acute cerebral infarction
TL;DR: Patients with acute stroke can be evaluated with CT and treated with streptokinase within 6 h, but the opportunity for treatment is currently limited to few patients.
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