Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
Chat about Author
Papers
Strengthening Acute Stroke Trials Through Optimal Use of Disability End Points
TL;DR: The RS and global end points are preferable to BI end points; the position of the cut point is also important.
52
Alteplase for Acute Ischemic Stroke in Patients Aged >80 Years: Pooled Analyses of Individual Patient Data.
TL;DR: Alteplase for AIS has a positive benefit-risk profile among patients aged >80 years when administered according to other regulatory criteria, and should be evaluated on an individual benefit- risk basis.
50
Percutaneous Closure of Patent Foramen Ovale in Patients With Paradoxical Embolism
TL;DR: It is suggested that young patients with cryptogenic stroke and large PFO should currently be referred for closure if unsuitable for anticoagulant therapy and that large randomized trials will be required to demonstrate a significant benefit of interventional techniques.
50
The Use of Embolic Signal Detection in Multicenter Trials to Evaluate Antiplatelet Efficacy Signal Analysis and Quality Control Mechanisms in the CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) Trial
Ralf Dittrich,Martin A. Ritter,Manfred Kaps,Mario Siebler,Kennedy R. Lees,Vincent Larrue,Darius G. Nabavi,E. Bernd Ringelstein,Hugh S. Markus,Dirk W. Droste +9 more
TL;DR: The present study aimed at installing primary and secondary quality control measures in CARESS because MES evaluation relies on subjective judgment by human experts and multicenter studies using MES as outcome parameter are feasible.
Statin administration prior to ischaemic stroke onset and survival: exploratory evidence from matched treatment-control study.
Stella Aslanyan,Christopher J. Weir,Gordon T. McInnes,J Reid,Matthew Walters,Kennedy R. Lees +5 more
TL;DR: The use of statins prior to stroke onset was associated with improved stroke survival within this cohort study with matched controls as mentioned in this paper, and the authors also found that statin use is associated with reduced mortality at 1 month and during the follow-up period (hazard ratio 0.57; 95% CI 0.35-0.93).
49