Kennedy R. Lees
University of Glasgow
467 Papers
3.9K Citations
Kennedy R. Lees is an academic researcher from University of Glasgow. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 86, co-authored 455 publications. Previous affiliations of Kennedy R. Lees include Ludwig Maximilian University of Munich & Cedars-Sinai Medical Center.
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Papers
Allopurinol reduces brachial and central blood pressure, and carotid intima-media thickness progression after ischaemic stroke and transient ischaemic attack: a randomised controlled trial
Peter Higgins,Matthew Walters,Heather Murray,Kate McArthur,Alex McConnachie,Kennedy R. Lees,Jesse Dawson +6 more
TL;DR: Allopurinol lowered CBP and reduced CIMT progression at 1 year compared with placebo in patients with recent ischaemic stroke and TIA, highlighting the potential for reduction in cardiovascular events with this treatment strategy.
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Safety and efficacy of thrombectomy in acute ischaemic stroke (REVASCAT): 1-year follow-up of a randomised open-label trial
Antoni Dávalos,Erik Cobo,Carlos A. Molina,Ángel Chamorro,M Angeles de Miquel,Luis San Roman,Joaquín Serena,Elena López-Cancio,Marc Ribó,Mónica Millán,Xabier Urra,Pere Cardona,Alejandro Tomasello,Carlos Castaño,Jordi Blasco,Lucia Aja,Marta Rubiera,Meritxell Gomis,Arturo Renú,Blanca Lara,Joan Martí-Fàbregas,Brian Jankowitz,Neus Cerdà,Tudor G Jovin,Marc Ribó,Estela Sanjuan,M. Rubiera,J. Pagola,Alan Flores,Marian Muchada,Pilar Meler,E. Huerga,S. Gelabert,Pilar Coscojuela,A. Tomasello,D. Rodriguez,Estevo Santamarina,Olga Maisterra,Sandra Boned,Laia Seró,Ana Rovira,Carlos A. Molina,M. Millán,L. Muñoz,N. Pérez de la Ossa,M. Gomis,Laura Dorado,E. López-Cancio,E. Palomeras,Josep Munuera,P. García Bermejo,Sebastian Remollo,C. Castaño,R. García-Sort,Patricia Cuadras,Paloma Puyalto,María Hernández-Pérez,Marta Jiménez,Alicia Martínez-Piñeiro,Giuseppe Lucente,Antonio Dávalos,A. Chamorro,X. Urra,Victor Obach,Álvaro Cervera,Sergio Amaro,Laura Llull,Javier Codas,Mircea Balasa,Joaquin Luis Navarro,Helena Ariño,A. Aceituno,Salvatore Rudilosso,A. Renu,Juan Macho,L. San Román,J. Blasco,Antonio M. López,Napoleon Macias,Pedro Cardona,Helena Quesada,Francisco Rubio,Luis Cano,B. Lara,MA de Miquel,L. Aja,Tudor G. Jovin,J. Serena,E. Cobo,Gregory W. Albers,Kennedy R. Lees,Juan F. Arenillas,R. Roberts,Mayank Goyal,Andrew M. Demchuk,P. Minhas,Fahad S. Al-Ajlan,M Salluzzi,L Zimmel,S. Patel,M. Eesa,R. von Kummer,J. Martí-Fàbregas,Brian T. Jankowitz,M. Salvat-Plana +104 more
TL;DR: At 12 months follow-up, neurovascular thrombectomy reduced post-stroke disability and improved health-related quality of life, indicating sustained benefit, have important clinical and public health implications for evaluating the cost-effectiveness of the intervention in the long term.
Differences in first dose response to angiotensin converting enzyme inhibition in congestive heart failure: a placebo controlled study.
TL;DR: This controlled study is the first to indicate a qualitative difference in the acute response to angiotensin converting enzyme inhibitors with similar structure and metabolism (that is, enalapril and perindopril), which seems to be less likely to cause hypotension in patients with heart failure.
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Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure
Issam A. Awad,Sean P. Polster,Julián Carrión-Penagos,Richard E. Thompson,Ying Cao,Agnieszka Stadnik,Patricia Lynn Money,Maged D Fam,Janne Koskimäki,Romuald Girard,Karen Lane,Nichol McBee,Wendy C. Ziai,Yi Hao,Robert L. Dodd,Andrew P. Carlson,Paul J. Camarata,Jean-Louis Caron,Mark R. Harrigan,Barbara A. Gregson,A. David Mendelow,Mario Zuccarello,Daniel F Hanley,Azmil Abdul-Rahim,Amal Abou-Hamden,Michael Abraham,Azam Ahmed,Carlos Alarcon Alba,E. Francois Aldrich,Hasan Ali,David Altschul,Sepideh Amin-Hanjani,Craig S. Anderson,Doug Anderson,Safdar Ansari,David Antezana,Agnieszka Ardelt,Fuat Arikan,Radhika Avadhani,Marcelino Báguena,Alexandra D Baker,Steven J. Barrer,Pál Barzó,Kyra J. Becker,Thomas A. Bergman,Joshua Betz,Amanda J. Bistran-Hall,Azize Boström,Jamie Braun,Peter Brindley,William C. Broaddus,Robert H. Brown,Andras Buki,Diederik Bulters,Bing Cao,J. Ricardo Carhuapoma,Julio A. Chalela,Tiffany R. Chang,Michael R. Chicoine,Indalecio Moran Chorro,Shakeel A. Chowdhry,Cully Cobb,Luisa Corral,Laszlo Csiba,Jason M Davies,Jesse Dawson,Alberto Torres Díaz,Colin P. Dierdeyn,Michael N. Diringer,Rachel Dlugash,Robert D. Ecker,Tracey Economas,Pedro Enriquez,Erzsebet Ezer,Yuhua Fan,Hua Feng,Douglas Franz,W. David Freeman,Matthew R. Fusco,Walter Galicich,Dheeraj Gandhi,Mary Leigh Gelea,Joshua N. Goldstein,Alejandro Carrasco Gonzalez,Christina Grabarits,Steven M. Greenberg,Daryl R. Gress,Eugene Gu,Gaurav Gupta,Christiana E. Hall,Sagi Harnof,Fernando Muñoz Hernandez,Robert Hoesch,Brian L. Hoh,Jennifer Houser,Rong Hu,Judy Huang,Yi Huang,Mohammed Hussain,Salvatore Insinga,Ashutosh P Jadhav,Jennifer Jaffe,Babak S. Jahromi,Jack Jallo,Michael L. James,Robert F James,Scott Janis,Brian T. Jankowitz,Esther Jeon,Draga Jichici,Karin Jonczak,Ben Jonker,Nicki Karlen,Carlos S. Kase,Naureen Keric,Thomas Kerz,Ryan S. Kitagawa,Jared Knopman,Carolyn Koenig,Satish Krishnamurthy,Avinash B. Kumar,Inam Kureshi,John Laidlaw,Arun Lakhanpal,Julius Gene Latorre,David Ledoux,Kennedy R. Lees,Dana Leifer,James Leiphart,Sarah Lenington,Yunke Li,George A. Lopez,Darren Lovick,Christianto B. Lumenta,Jinbiao Luo,Matthew B. Maas,Joel D. MacDonald,Larami MacKenzie,Vikram Madan,Ryan Majkowski,Ottó Major,Rishi Malhorta,Marc D. Malkoff,Halinder S. Mangat,Ahmed Maswadeh,Charles C. Matouk,Steven Mayo,Kate McArthur,Scott McCaul,Joshua E. Medow,Geza Mezey,Janet Mighty,David Miller,Patrick Mitchell,Krishna K. Mohan,W. Andrew Mould,Keith W. Muir,Lorenzo F. Munoz,Peter Nakaji,Alex Nee,Saman Nekoovaght-Tak,Paul A. Nyquist,Roddy O'Kane,Mohamed Okasha,Cian O'Kelly,Noeleen Ostapkovich,Aditya S. Pandey,Adrian R Parry-Jones,Hiren C. Patel,Krissia Rivera Perla,Ania Pollack,Nader Pouratian,Terry Quinn,Ventatakrishna Rajajee,Kesava Reddy,Mohammed Rehman,Ronald Reimer,Fred Rincon,Michael Rosenblum,Igor Rybinnik,Baltasar Sanchez,Lauren H Sansing,Rosario Sarabia,Michael Schneck,Ludwig Schuerer,David Schel,Jeffrey S. Schweitzer,David B. Seder,Donald Seyfried,Kevin N. Sheth,Alejandro M Spiotta,Michael T. Stechison,Elizabeth A. Sugar,Katalin Szabo,Gonzalo Tamayo,Krisztian Tanczos,Philipp Taussky,Jeanne Teitelbaum,John Terry,Fernando D. Testai,Kathrine Thomas,Carol B. Thompson,Gregory Thompson,James C. Torner,Huy Tran,Kristi Tucker,Natalie Ullman,Lior Ungar,Andreas Unterberg,Panos Varelas,Nataly Montano Vargas,Hartmut Vatter,Chitra Venkatasubramanian,Krista Vermillion,Paul M. Vespa,Dennis G. Vollmer,Weimin Wang,Yan Wang,Ying Wang,Jiajun Wen,Louis Tony Whitworth,Byron Willis,Alastair Wilson,Stacey Q Wolfe,Myriha Wrencher,Shawn E. Wright,Yongge Xu,Lisa Yanase,Gayane Yenokyan,Xuxia Yi,Zhiyuan Yu,Ali R. Zomorodi +231 more
TL;DR: This is the first surgical trial reporting thresholds for reduction of ICH volume correlating with improved mortality and functional outcomes, and is likely to be the first to achieve this goal.
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Effect of B Vitamins and Lowering Homocysteine on Cognitive Impairment in Patients With Previous Stroke or Transient Ischemic Attack A Prespecified Secondary Analysis of a Randomized, Placebo-Controlled Trial and Meta-Analysis
Graeme J. Hankey,Andrew H. Ford,Qilong Yi,John W. Eikelboom,Kennedy R. Lees,Christopher Chen,Denis Xavier,Jose C. Navarro,Udaya K. Ranawaka,Wasim Uddin,Stefano Ricci,John Gommans,R. Schmidt,Osvaldo P. Almeida,F.M. van Bockxmeer +14 more
TL;DR: Daily supplementation with folic acid, vitamin B6, and vitamin B12 to a self-selected clinical trial cohort of cognitively unimpaired patients with previous stroke or transient ischemic attack lowered mean tHcy but had no effect on the incidence of cognitive impairment or cognitive decline, as measured by the MMSE, during a median of 2.8 years.
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