Kenine E. Comstock
University of North Carolina at Chapel Hill
2 Papers
76 Citations
Kenine E. Comstock is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Provirus & Gene. The author has an hindex of 2, co-authored 2 publications.
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Papers
Killing Epstein-Barr virus-positive B lymphocytes by gene therapy: comparing the efficacy of cytosine deaminase and herpes simplex virus thymidine kinase
Robert P. Rogers,Ji-Qian Ge,Elizabeth Holley-Guthrie,Diana K. Hoganson,Kenine E. Comstock,John C. Olsen,Shannon C. Kenney +6 more
TL;DR: The sum of the data indicates that the CD/5-FC combination is the more promising regimen for treatment of EBV-associated lymphomas in vivo, despite having a significantly greater therapeutic margin than the HSV-TK/ganciclovir combination.
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Design of Retroviral Expression Vectors
TL;DR: Several characteristics of amphotropic murine retroviruses have made them useful as vectors for gene transfer with some distinct advantages over other methods of transduction, including a broad host range, and retroviral vectors can be conveniently manipulated in plasmid form and are somewhat flexible in terms of vector design.
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