Kenhiro Rin
Kyoto Prefectural University of Medicine
18 Papers
15 Citations
Kenhiro Rin is an academic researcher from Kyoto Prefectural University of Medicine. The author has contributed to research in topics: Arachidonic acid & Prostacyclin. The author has an hindex of 2, co-authored 18 publications.
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Papers
Effect of Ca antagonists on PGI2 generation in cultured human vascular endothelial cells
Takeo Toyoda,Shohei Sawada,Isamu Niwa,Norihiko Maebo,Hajime Tsuji,Kinji Mikami,Kenhiro Rin,Masao Nakagawa,Hamao Ijichi +8 more
TL;DR: The PGI2 generation induced by A-23187, Arachidonic acid, or PGH2 was remarkably decreased by preincubating the cells with TMB-8 and addition of Diltiazem had no effect.
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Effects of vasodilators on the platelet aggregation and PGI2 generation of vessel wall
Yoshiharu Maeda,Shunyo Kanayama,Kichiro Osamura,Kenhiro Rin,Yasushi Okajima,Tsunehiro Kawamura,Teruo Kitani,Mitsuro Watada,Masao Nakagawa,Hamao Ijichi +9 more
TL;DR: Results indicate that Verapamil increases the PGI2 generation in the process of A. A. metabolism, and it is suspected that Ca-antagonist affects the process after liberation of arachidonic acid.
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Effect of nitroglycerine on PGI2 generation in cultured human vascular endothelial cells
Isamu Niwa,Norihiko Maebo,Ryo Okano,Kinji Mikami,Takeo Toyoda,Kenhiro Rin,Kichiro Osamura,Teruo Kitani,Masao Nakagawa,Hamao Ijichi +9 more
TL;DR: The results indicate that the increase in PGI2 generation in the vascular endothelial cells by NTG may contribute to the vasodilating activity chiefly through the activation of phospholipase A2 in the arachidonic acid cascade, without influencing on the level of intracellurar cAMP.
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Effect of vasodilators on prostacyclin synthesis of cultured human umbilical endothelial cells
Takeo Toyoda,Ryo Okano,Kinji Mikami,Shunyo Kanayama,Hajime Tsuji,Kichiro Osamura,Kenhiro Rin,Isao Kaimasu,Masao Nakagawa,Hamao Ijichi +9 more
TL;DR: Effect of these vasodilators was possibly developed by the increase of prostacyclin synthesis from endothelial cells, and this effect demonstrated an inhibitory effect for ADP induced platelet aggregation.
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