Ken Masuguchi
Kyushu University
9 Papers
135 Citations
Ken Masuguchi is an academic researcher from Kyushu University. The author has contributed to research in topics: Hyperalgesia & Peripheral neuropathy. The author has an hindex of 6, co-authored 8 publications.
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Papers
Goshajinkigan reduces oxaliplatin-induced peripheral neuropathy without affecting anti-tumour efficacy in rodents
Soichiro Ushio,Nobuaki Egashira,Hikaru Sada,Takehiro Kawashiri,Masafumi Shirahama,Ken Masuguchi,Ryozo Oishi +6 more
TL;DR: Results suggest that GJG relieves the oxaliplatin-induced cold hyperalgesia and mechanical allodynia without affecting anti-tumour activity of oxali Platin, and, therefore, may be useful for theOxaliplin-induced neuropathy in clinical practice.
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Inhibition of Ca2+/calmodulin-dependent protein kinase II reverses oxaliplatin-induced mechanical allodynia in rats.
Masafumi Shirahama,Soichiro Ushio,Nobuaki Egashira,Shota Yamamoto,Hikaru Sada,Ken Masuguchi,Takehiro Kawashiri,Ryozo Oishi +7 more
TL;DR: Investigation of the involvement of Ca2+/calmodulin dependent protein kinase II (CaMKII) in the oxaliplatin-induced mechanical allodynia in rats suggests that CaMKII is involved in theOxali Platin- induced mechanicalAllodynia, and trifluoperazine may be useful for the treatment of oxaliplant-induced peripheral neuropathy in clinical setting.
Exenatide Facilitates Recovery from Oxaliplatin-Induced Peripheral Neuropathy in Rats
Shunsuke Fujita,Soichiro Ushio,Nana Ozawa,Ken Masuguchi,Takehiro Kawashiri,Ryozo Oishi,Nobuaki Egashira +6 more
TL;DR: Exenatide may be useful for treating peripheral neuropathy induced by oxaliplatin in colorectal cancer patients with type 2 diabetes, and facilitated recovery from the oxali platin-induced neuropathy with reparation of axonal degeneration.
Neurotropin® relieves oxaliplatin-induced neuropathy via Gi protein-coupled receptors in the monoaminergic descending pain inhibitory system
Ken Masuguchi,Hitomi Watanabe,Takehiro Kawashiri,Soichiro Ushio,Nana Ozawa,Haruka Morita,Ryozo Oishi,Nobuaki Egashira +7 more
TL;DR: It is suggested that neurotropin is effective in relieving oxaliplatin-induced neuropathy, and that Gi protein-coupled receptors in the monoaminergic descending pain inhibitory system may be involved in the analgesic effect of neurotrop in rats.
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Comparison of peripheral neuropathy induced by standard and nanoparticle albumin-bound paclitaxel in rats.
TL;DR: The results suggest that closer attention must be paid to the neuropathy when administering nab-paclitaxel in clinical settings, and the effects of nab- paclitAXel on pain behaviors tended to be stronger than that of standard paclitaxe at the doses used clinically.
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