Keisuke Takanashi
Chiba University
6 Papers
18 Citations
Keisuke Takanashi is an academic researcher from Chiba University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 3 publications.
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Papers
FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
TL;DR: Findings indicate SAFB1 could be a FUS’s functional platform in chromatin compartment to regulate RNA splicing and ligand-dependent transcription and shed light on the etiological significance of nuclear matrix-associated proteins in ALS pathogenesis.
Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation.
TL;DR: Findings raise the possibility that ALS-linked C-terminal FUS mutants could sequester a variety of RNA binding proteins and mRNAs in the cytoplasmic aggregates, which could disrupt various aspects of RNA equilibrium and biogenesis.
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Treatment with a Global Methyltransferase Inhibitor Induces the Intranuclear Aggregation of ALS-Linked FUS Mutant In Vitro
TL;DR: Findings indicated the treatment with a methylation inhibitor at the appropriate levels could alleviate the cytoplasmic mislocalization but in excess this could cause the intranuclear aggregation of FUS C-terminal mutant.
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Clinical outcome of drug-coated balloons in patients with femoropopliteal chronic total occlusive lesions: results from the multicenter EAGLE study
Naoki Hayakawa,Mitsuyoshi Takahara,Tatsuya Nakama,Kazunori Horie,Keisuke Takanashi,Teruaki Kanagami,Shinya Ichihara,Masataka Arakawa,Kazuki Tobita,Shinsuke Mori,Yousuke Iwata,Kenji Suzuki,Junji Kanda +12 more
TL;DR: In this article , the authors investigated the clinical outcomes of drug-coated balloon (DCB) for femoropopliteal (FP) chronic total occlusive lesions (CTO) and found that DCB treatment was effective in real-world clinical practice.
Optimal intraluminal drug-coated balloon versus drug-eluting stent in patients with chronic total occlusion of the superficial femoral artery: A retrospective analysis.
Naoki Hayakawa,Satoshi Kodera,Keisuke Takanashi,Teruaki Kanagami,Shinya Ichihara,Masataka Arakawa,Satoshi Hirano,Yasunori Inoguchi,Sandeep Shakya,Junji Kanda +9 more
TL;DR: In this article , the authors compared the clinical outcome of high-dose drug-coated balloon (DCB) with successful lesion preparation and DES in CTO of the superficial femoral artery (SFA).
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