Keisuke Kamimura
Institute of Medical Science
18 Papers
136 Citations
Keisuke Kamimura is an academic researcher from Institute of Medical Science. The author has contributed to research in topics: Heparan sulfate & Perlecan. The author has an hindex of 10, co-authored 18 publications. Previous affiliations of Keisuke Kamimura include University of Minnesota.
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Papers
Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling.
Keisuke Kamimura,Takashi Koyama,Hiroko Habuchi,Ryu Ueda,Masayuki Masu,Koji Kimata,Hiroshi Nakato +6 more
TL;DR: It is found that mutations in Hs2st or Hs6st had unexpectedly little effect on tracheal morphogenesis, and the overall sulfation level is more important than strictly defined HS fine structures for FGF signaling in some developmental contexts.
Functions of Chondroitin Sulfate and Heparan Sulfate in the Developing Brain
TL;DR: Recent studies have begun to reveal that the molecular interactions mediated by such glycosaminoglycan microdomains play critical roles in the various signaling pathways essential for the development of the brain.
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Regulation of Notch signaling by Drosophila heparan sulfate 3-O sulfotransferase.
Keisuke Kamimura,John Rhodes,Ryu Ueda,Melissa McNeely,Deepak Shukla,Koji Kimata,Patricia G. Spear,Nicholas W. Shworak,Hiroshi Nakato +8 more
TL;DR: It is shown that Drosophila melanogaster HS 3-O sulfotransferase-b (Hs3st-B) is a novel component of the Notch pathway, and levels of Notch protein on the cell surface were markedly decreased by loss of Hs3th-B.
Perlecan regulates bidirectional Wnt signaling at the Drosophila neuromuscular junction
TL;DR: Perlecan/Trol at the neuromuscular junction suppresses presynaptic canonical Wg signaling but enhances the postsynaptic Frizzled nuclear import pathway.
Glypicans and Heparan Sulfate in Synaptic Development, Neural Plasticity, and Neurological Disorders.
Keisuke Kamimura,Nobuaki Maeda +1 more
TL;DR: The role of glypicans and heparan sulfate proteoglycans (HSPGs) in the development and function of synapses has been extensively studied in the literature as discussed by the authors.