Kee Heng
University of Adelaide
14 Papers
32 Citations
Kee Heng is an academic researcher from University of Adelaide. The author has contributed to research in topics: Leydig cell & Internal medicine. The author has an hindex of 9, co-authored 11 publications.
Chat about Author
Papers
Dynamics of INSL3 Peptide Expression in the Rodent Testis
TL;DR: The secretion of INSL3 into peripheral blood in mice and during postnatal male rat development is mapped, indicating an “overshoot” effect in the establishment of Leydig cell functionality during the first wave of spermatogenesis.
93
Insulin-Like Factor 3 and the HPG Axis in the Male
TL;DR: Insulin-like peptide 3 (INSL3) represents an additional and different endpoint of the HPG axis and serves as an excellent marker for Leydig cell differentiation and functional capacity, as in puberty, or in monitoring the treatment of hypogonadal patients, and at the same time buffering theHPG output.
Circulating insulin-like factor 3 (INSL3) in healthy and infertile women
Ravinder Anand-Ivell,Ravinder Anand-Ivell,Kelton Tremellen,Yanzhenzi Dai,Kee Heng,M. Yoshida,Philip G. Knight,G.E. Hale,Richard Ivell,Richard Ivell +9 more
TL;DR: It is shown for the first time that INSL3 in women does vary across the menstrual cycle, and appears to reflect the number of growing antral follicles recruited within both follicular and luteal phases.
Relaxin signalling in primary cultures of human myometrial cells
TL;DR: It is shown that relaxin is able to stimulate the generation of cAMP in a manner, which is dependent upon a tyrosine phosphorylation activity, as in the endometrium, and the inability of relaxin to inhibit contractility in human myometrial cells would appear to be due to events downstream of simple cAMP generation.
38
The endocrine disruptors dibutyl phthalate (DBP) and diethylstilbestrol (DES) influence Leydig cell regeneration following ethane dimethane sulphonate treatment of adult male rats.
Kee Heng,Ravinder Anand-Ivell,Ravinder Anand-Ivell,Katja J. Teerds,Richard Ivell,Richard Ivell +5 more
TL;DR: Both DBP and DES are able to affect adult-type Leydig cells during their differentiation to cause a significant perturbation in their ultimate functional capacity.
38