4 Papers
Ke Yang is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Prodrug & Chemistry. The author has an hindex of 2, co-authored 2 publications.
Chat about Author
Papers
International Journal of Pharmaceutics
Wei He,Ke Yang,Li-Fang Fan,Yaqi Lv,Zhu Jin,Shumin Zhu,Chao Qin,Yiao Wang,Lifang Yin +8 more
- 01 Jan 2015
TL;DR: The International Journal of Pharmaceutics is the journal for pharmaceutical scientists concerned with the physical, chemical and biological properties of devices and delivery systems for drugs, vaccines and biologicals, including their design, manufacture and evaluation.
355
Denatured globular protein and bile salt-coated nanoparticles for poorly water-soluble drugs: Penetration across the intestinal epithelial barrier into the circulation system and enhanced oral bioavailability.
TL;DR: A new nanoemulsion system with a denatured globular protein with a diameter of 30 nm, soybean protein isolates, and bile salt as emulsifiers, aiming to enhance the absorption of insoluble drugs and explore other pathways for absorption, significantly improved FB oral absorption.
23
A supramolecular nano-delivery system based on AIE PARP inhibitor prodrug and glycosylated pillar[5]arene for drug-resistance therapy.
Manman Yang,Ke Yang,Bingling Gao,Peng Wang,Tianjiao Li,Yi Zheng,Yuxin Pei,Zhichao Pei,Yinghua Lv +8 more
TL;DR: In vitro studies revealed that the DOX-loaded GP5⊃Pro-ANI achieved targeted drug delivery and dual-drug synergistic chemotherapy for DNA repair interference and tumor DNA collapse aggravation, which enhanced the chemosensitivity and overcame tumor drug resistance and migration.
10
Supramolecular nanoprodrug based on a chloride channel blocker and glycosylated pillar[5]arenes for targeted chemoresistance cancer therapy.
TL;DR: A supramolecular nanoprodrug (DOX@GP5⊃Pro-NFA) was constructed based on the host-guest complexation of chloride channel blocker prodrug and glycosylated pillar[5]arene (GP5), which could target tumor cells via galactose and release DOX/NFA responsively under esterase stimulation as mentioned in this paper .
10