Ke Wu
4 Papers
Ke Wu is an academic researcher. The author has contributed to research in topics: Phosphorylation & Medicine. The author has an hindex of 2, co-authored 4 publications.
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Papers
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function
Ke Wu,Meisi Yan,Tong-Xin Liu,Zheng-Hua Wang,Yu-Qiu Duan,Yan Xia,Guimei Ji,Yuling Shen,Lei Wang,Lin Li,Peixiang Zheng,Bofei Dong,Qingang Wu,Liwei Xiao,Xueying Yang,Hao-Miao Shen,Jingjing Zhang,Jinfeng Yi,Yu-Yi Deng,Xu Qian,Leina Ma,Jing Fang,Qingxin Zhou,Zhimin Lu,Daqian Xu +24 more
TL;DR: Findings reveal a critical mechanism by which tumour cells counteract ferroptosis by non-metabolic function of C KB-enhanced GPX4 stability and underscore the potential to target the protein kinase activity of CKB for cancer treatment.
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Synthesizing and characterizing Fe3O4 embedded in N-doped carbon nanotubes-bridged biochar as a persulfate activator for sulfamethoxazole degradation
Tong Liu,Qi Wang,Chenxuan Li,Minshu Cui,Yawen Chen,Ruiqiang Li,Kangping Cui,Ke Wu,Xianbao Nie,Sanliu Wang +9 more
TL;DR: In this article , the airtight structure of iron oxide (Fe 3 O 4 ) nanoparticles embedded in N-doped CNTs (NCNTs) was supported by biochar (BC) that could both promote electron transfer and avoid large amounts of metal leaching.
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Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth
Zheng-Hua Wang,Min Li,Hongfei Jiang,Shudi Luo,Fei Shao,Yan Xia,Meng-qing Yang,Xiangle Ren,Tong-Xin Liu,Meisi Yan,Xu Qian,Haiyan He,Dong Guo,Yu-Qiu Duan,Ke Wu,Lei Wang,Guimei Ji,Yu-liang Shen,Lin Li,Peixiang Zheng,Bofei Dong,Jing Fang,Min Zheng,Tingbo Liang,Haitao Li,Rilei Yu,Daqian Xu,Zhimin Lu +27 more
TL;DR: It is demonstrated that glucose deprivation in normal hepatocytes induces PERK-mediated fructose-1,6-bisphosphatase 1 (FBP1) S170 phosphorylation, which converts the FBP1 tetramer to monomers and exposes its nuclear localization signal for nuclear translocation.
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Nucleus-exported CLOCK acetylates PRPS to promote de novo nucleotide synthesis and liver tumour growth
Tong Liu,Zheng-Hua Wang,Leiguang Ye,Yu-Qiu Duan,Hongfei Jiang,Haiyan He,Liwei Xiao,Qingang Wu,Yan Xia,Meng-qing Yang,Ke Wu,Meisi Yan,Guimei Ji,Yuling Shen,Lei Wang,Lin Li,Peixiang Zheng,Bofei Dong,Fei Shao,Xu Qian,Rilei Yu,Zhiren Zhang,Zhimin Lu,Daqian Xu +23 more
TL;DR: A critical mechanism by which oncogenic signalling inhibits canonical CLOCK transcriptional activity and simultaneously confers CLOCK with instrumental moonlighting functions to promote nucleotide synthesis and tumour growth is delineated.