Kazuhiko Takai
Okayama University
375 Papers
3.8K Citations
Kazuhiko Takai is an academic researcher from Okayama University. The author has contributed to research in topics: Catalysis & Rhenium. The author has an hindex of 52, co-authored 372 publications. Previous affiliations of Kazuhiko Takai include Kyoto University & University of Tokyo.
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Papers
Generation of a Geminal Dicarbenoid of Chromium: Formation of Allenes from Terminal Alkenes in One-Pot.
TL;DR: In this paper, a geminal dicarbenoid of chromium was generated by reduction of two of the chlorine atoms of CCl 4, which selectively reacts with terminal olefins to givecyclopropylidene carbenoids, which readily decompose to allenes.
Indium-Catalyzed Synthesis of Keto Esters from Cyclic 1,3-Diketones and Alcohols and Application to the Synthesis of Seratrodast.
Yoichiro Kuninobu,Atsushi Kawata,Taihei Noborio,Syun Ichi Yamamoto,Takashi Matsuki,Kazumi Takata,Kazuhiko Takai +6 more
TL;DR: In this article, the carbon-carbon bond cleavage by a retro-aldol reaction was applied to the preparation of the keto esters during the synthesis of seratrodast, which is an antiasthmatic and eicosanoid antagonist.
Three-Component Coupling Reactions of Alkyl Iodides, 1,3-Dienes, and Carbonyl Compounds by Sequential Generation of Radical and Anionic Species with CrCl2.
TL;DR: The mild reductant chromium(II) chloride can discriminate between alkyl iodides, alkyls radicals, and allylic radicals as mentioned in this paper, and it can undergo intermolecular addition to a 1,3-diene.
Isocyanate Acting as a Carbonyl Precursor: Pyridyl Group Assisted Formation of 4H-Pyrido[1,2-a]pyrimidin-4-ones from Ketimines and Isocyanates.
TL;DR: The pyridyl or picolyl group is a key functional group because it is not only the constituent structure of the 4H-pyrido[1,2-a]pyrimidin-4-one framework but also the promoter of the formation of a ketene intermediate as mentioned in this paper.
Reaction of Tantalum‐Alkyne Complexes with Isocyanates or Acyl Cyanides. Stereoselective Functionalization of Carbon‐Carbon Triple Bonds.
Yasutaka Kataoka,Yoshiyuki Oguchi,Kazuyuki Yoshizumi,Seiji Miwatashi,Kazuhiko Takai,Kiitiro Utimoto +5 more
TL;DR: The tantalum-alkyne complexes also react with acyl cyanides in the presence of BF3·OEt2 to give α-cyanohydrins as mentioned in this paper.