Kazuhiko Ino
Wakayama Medical University
195 Papers
1.8K Citations
Kazuhiko Ino is an academic researcher from Wakayama Medical University. The author has contributed to research in topics: Medicine & Ovarian cancer. The author has an hindex of 39, co-authored 189 publications. Previous affiliations of Kazuhiko Ino include Nagoya University.
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Papers
Comprehensive Gene Mutation Profiling of Circulating Tumor DNA in Ovarian Cancer: Its Pathological and Prognostic Impact.
Tomoko Noguchi,Naoyuki Iwahashi,Kazuko Sakai,Kaho Matsuda,Hitomi Matsukawa,Saori Toujima,Kazuto Nishio,Kazuhiko Ino +7 more
TL;DR: The comprehensive gene mutation profiles of ct DNA in 51 patients with different histological subtypes of stage I–IV ovarian cancer, and their association with clinical outcomes suggest that ctDNA-based gene profiling may serve as a prognostic indicator and might help in establishing personalized therapeutic strategies for ovarian cancer.
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Growth inhibitory effect of bestatin on choriocarcinoma cell lines in vitro
Kazuhiko Ino,Setsuko Goto,Akemi Kosaki,Seiji Nomura,Eiko Asada,Toshiya Misawa,Yoshihito Furuhashi,Shigehiko Mizutani,Yutaka Tomoda +8 more
TL;DR: The results suggest that bestatin has not only an indirect host-mediated anti-tumor activity, but also a direct growth-inhibitory effect on some kinds of cancer cell lines.
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Tocilizumab Inhibits Interleukin-6-Mediated Matrix Metalloproteinase-2 and -9 Secretions from Human Amnion Cells in Preterm Premature Rupture of Membranes
Yukio Mano,Kiyosumi Shibata,Seiji Sumigama,Hiromi Hayakawa,Kazuhiko Ino,Eiko Yamamoto,Hiroaki Kajiyama,Akihiro Nawa,Fumitaka Kikkawa +8 more
TL;DR: This paper is the 1st report of tocilizumab inhibiting IL-6-induced M MP-2 and MMP-9 secretions from human amnion cells in PPROM.
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Ultrastructural localization of aminopeptidase A/angiotensinase and placental leucine aminopeptidase/oxytocinase in chorionic villi of human placenta
Norio Ito,Seiji Nomura,Akira Iwase,Tomomi Ito,Kazuhiko Ino,Tetsuo Nagasaka,Masafumi Tsujimoto,Miya Kobayashi,Shigehiko Mizutani +8 more
TL;DR: The observation that P-LAP and APA are present on the microvilli, which is a site of interaction between the mother and fetus, suggests possible involvement of these enzymes in cleaving peptide hormones from the fetus and mother in order to regulate bioactivity.
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Establishment and Characterization of an Ovarian Yolk Sac Tumor Cell Line Reveals Possible Involvement of Nkx2.5 in Tumor Development
Kiyosumi Shibata,Hiroaki Kajiyama,Eiko Yamamoto,Mikio Terauchi,Kazuhiko Ino,Akihiro Nawa,Fumitaka Kikkawa +6 more
TL;DR: Analysis of this new cell line suggested that Nkx2.5 can be a new molecular target in the treatment of ovarian YST, the first report of a cell line established from human YST.
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