Kazue Ise
Tohoku Pharmaceutical University
36 Papers
83 Citations
Kazue Ise is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Medicine & Aldosterone. The author has an hindex of 12, co-authored 27 publications. Previous affiliations of Kazue Ise include Tohoku University.
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Papers
Histopathological Classification of Cross-Sectional Image-Negative Hyperaldosteronism.
Yuto Yamazaki,Yasuhiro Nakamura,Kei Omata,Kazue Ise,Yuta Tezuka,Yoshikiyo Ono,Ryo Morimoto,Yukinaga Nozawa,Celso E. Gomez-Sanchez,Celso E. Gomez-Sanchez,Scott A. Tomlins,William E. Rainey,Sadayoshi Ito,Fumitoshi Satoh,Fumitoshi Satoh,Hironobu Sasano +15 more
TL;DR: In this paper, the detailed histopathologic, steroidogenic and pathobiological features of cross-sectional image negative primary aldosteronism (PA) have not been well characterized.
Adrenal CYP11B1/2 expression in primary aldosteronism: immunohistochemical analysis using novel monoclonal antibodies.
Yasuhiro Nakamura,Takashi Maekawa,Saulo J.A. Felizola,Fumitoshi Satoh,Xin Qi,Carolina Velarde-Miranda,Maria W. Plonczynski,Kazue Ise,Kumi Kikuchi,William E. Rainey,Elise P. Gomez-Sanchez,Celso E. Gomez-Sanchez,Hironobu Sasano +12 more
TL;DR: Findings did indicate the regulatory mechanisms of aldosterone biosynthesis were different between normal/hyperplastic and neoplastic ald testosterone-producing cells in human adrenals, and CYP11B2 immunoreactivity in the ZG could also serve as a potential immunohistochemical marker differentiating morphologically hyperplastic ZG of IHA and APA adjacent adrenal.
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Adrenocortical Carcinoma: Review of the Pathologic Features, Production of Adrenal Steroids, and Molecular Pathogenesis
Yasuhiro Nakamura,Yuto Yamazaki,Saulo J.A. Felizola,Kazue Ise,Ryo Morimoto,Fumitoshi Satoh,Yoichi Arai,Hironobu Sasano +7 more
TL;DR: The current status of the histopathological diagnosis, molecular pathogenesis, and hormonal features of ACC are summarized.
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Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17
Yasuhiro Nakamura,Masaaki Kitada,Fumitoshi Satoh,Takashi Maekawa,Ryo Morimoto,Yuto Yamazaki,Kazue Ise,Celso E. Gomez-Sanchez,Sadayoshi Ito,Yoichi Arai,Mari Dezawa,Hironobu Sasano +11 more
TL;DR: The presence of hybrid cells indicated the marked intratumoral heterogeneity of steroidogenesis in APAs, particularly in those producing glucocorticoids and mineralocortioids.
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An activation of LC3A‐mediated autophagy contributes to de novo and acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma
Kaito Nihira,Yasuhiro Miki,Shinya Iida,Sodai Narumi,Katsuhiko Ono,Erina Iwabuchi,Kazue Ise,Kazushige Mori,Mikiyoshi Saito,Masahito Ebina,Ikuro Sato,Makoto Maemondo,Hisafumi Yamada-Okabe,Takashi Kondo,Hironobu Sasano +14 more
TL;DR: It is demonstrated thatLC3A‐mediated autophagy in carcinoma cells was involved in the development of resistance to EGFR‐TKIs, and that LC3A could serve as a promising therapeutic target for overcoming resistance toEGFR‐ TKIs and a novel predictor of response to EG FR‐TkIs in lung adenocarcinoma patients.
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