Kazim Sahin
Fırat University
333 Papers
987 Citations
Kazim Sahin is an academic researcher from Fırat University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 54, co-authored 289 publications. Previous affiliations of Kazim Sahin include Dicle University & İnönü University.
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Papers
A Next Generation Formulation of Curcumin Ameliorates Experimentally Induced Osteoarthritis in Rats via Regulation of Inflammatory Mediators.
Mehmet Yabas,Cemal Orhan,Besir Er,Mehmet Tuzcu,Ali Durmus,Ibrahim Hanifi Ozercan,Nurhan Sahin,Prakash Bhanuse,Abhijeet Morde,Muralidhara Padigaru,Kazim Sahin +10 more
TL;DR: In this paper, a Next Generation Ultrasol Curcumin (NGUC) formulation of curcumin with enhanced bioavailability was proposed to improve the pathophysiology of osteoarthritis.
Rejuveinix Mitigates Sepsis-Associated Oxidative Stress in the Brain: Clinical Impact Potential in COVID-19 and Nervous System Disorders
Fatih M. Uckun,Mehmet Tuzcu,M. Gitterle,Michael Volk,Kazim Sahin +4 more
- 13 May 2021
TL;DR: It is demonstrated that the anti-sepsis drug candidate Rejuveinix (RJX), at a dose level that is >10-times lower than its maximum tolerated dose (MTD) for human subjects, improves the survival outcome in the LPS-GalN model of sepsis and multi-organ failure.
Epigallocatechin-3-gallate exerts protective effects against heat stress through modulating stress-responsive transcription factors in poultry
TL;DR: In this paper, the effect of Epigallocatechin-3-gallate (EGCG), a polyphenol derived from green tea, on activator protein-1 (AP-1) components (phospho-c-Jun and c-Fos), cyclooxygenase-2 (COX-2) and heat shock proteins (HSPs) in the liver of heat-stressed quails was described.
Proteasome inhibition prevents development of experimental dermal fibrosis.
Süleyman Serdar Koca,Metin Ozgen,Ferda Dagli,Mehmet Tuzcu,Ibrahim Hanifi Ozercan,Kazim Sahin,Ahmet Isik +6 more
TL;DR: In BLM-induced dermal fibrosis, bortezomib has a preventive anti-fibrotic and anti-inflammatory efficacy, but has no therapeutic anti-tissue fibrosis efficacy in preexisting tissue fibrosis.
The effect of oral administration of undenatured type II collagen on monosodium iodoacetate-induced osteoarthritis in young and old rats
Emre Şahin,Cemal Orhan,Fusun Erten,Zainulabedin M. Saiyed,Elnaz Karimian Azari,Shane Durkee,Kazim Sahin +6 more
TL;DR: In this paper , the authors investigated whether different doses of undenatured type II collagen (undenatured collagen, UC-II) help improve monosodium iodoacetate (MIA)-induced (osteoarthritis) OA in young and old rats.