Kaylyn E. Williamson
Harvard University
3 Papers
6 Citations
Kaylyn E. Williamson is an academic researcher from Harvard University. The author has contributed to research in topics: Enhancer & Chromatin. The author has an hindex of 3, co-authored 3 publications. Previous affiliations of Kaylyn E. Williamson include Broad Institute & Howard Hughes Medical Institute.
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Papers
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma
Yotam Drier,Yotam Drier,Yotam Drier,Matthew J. Cotton,Matthew J. Cotton,Matthew J. Cotton,Kaylyn E. Williamson,Kaylyn E. Williamson,Kaylyn E. Williamson,Shawn M. Gillespie,Shawn M. Gillespie,Shawn M. Gillespie,Russell J.H. Ryan,Russell J.H. Ryan,Russell J.H. Ryan,Michael J. Kluk,Christopher D. Carey,Scott J. Rodig,Lynette M. Sholl,A. Afrogheh,William C. Faquin,Lurdes Queimado,Jun Qi,Michael J. Wick,Adel K. El-Naggar,James E. Bradner,James E. Bradner,Christopher A. Moskaluk,Jon C. Aster,Birgit Knoechel,Birgit Knoechel,Bradley E. Bernstein,Bradley E. Bernstein,Bradley E. Bernstein +33 more
TL;DR: This study identifies super-enhancer translocations that drive MYB expression and provides insight into downstream MYB functions in alternate ACC lineages.
Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Gabriel J. Sandoval,Gabriel J. Sandoval,John L. Pulice,John L. Pulice,Hubert Pakula,Hubert Pakula,Monica Schenone,David Y. Takeda,David Y. Takeda,Marius S. Pop,Marius S. Pop,Gaylor Boulay,Gaylor Boulay,Kaylyn E. Williamson,Kaylyn E. Williamson,Matthew J. McBride,Matthew J. McBride,Joshua Pan,Joshua Pan,Roodolph St. Pierre,Emily C. Hartman,Levi A. Garraway,Levi A. Garraway,Steven A. Carr,Miguel Rivera,Miguel Rivera,Zhe Li,Zhe Li,Lucienne Ronco,William C. Hahn,William C. Hahn,Cigall Kadoch,Cigall Kadoch +32 more
TL;DR: It is found that ERG drives genome-wide retargeting of BAF complexes in a manner dependent on binding of ERG to the ETS DNA motif, which suggests a fundamental interdependence between ETS transcription factors and BAF chromatin remodeling complexes in cancer.
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Identification of promoter targets of enhancers by epigenetic knockdown using TAL DNA binding proteins
Eric M. Mendenhall,Eric M. Mendenhall,Kaylyn E. Williamson,Kaylyn E. Williamson,Deepak Reyon,J. Keith Joung,Bradley E. Bernstein,Bradley E. Bernstein +7 more
TL;DR: A fundamental question in biology is how an organism’s genome controls cellular differentiation and identity to produce numerous distinct cell types, and this work designed TALs to target over 50 putative distal enhancers to relatively quantitate the contribution on transcriptional activation of the target enhancer.