Kaylyn Devlin
Oregon Health & Science University
18 Papers
3 Citations
Kaylyn Devlin is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Extracellular matrix & Medicine. The author has an hindex of 3, co-authored 7 publications.
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Papers
The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations
Alexandra B Keenan,Sherry L. Jenkins,Kathleen M. Jagodnik,Simon Koplev,Edward He,Denis Torre,Zichen Wang,Anders B. Dohlman,Moshe C. Silverstein,Alexander Lachmann,Maxim V. Kuleshov,Avi Ma'ayan,Vasileios Stathias,Raymond Terryn,Daniel J. Cooper,Michele Forlin,Amar Koleti,Dusica Vidovic,Caty Chung,Stephan C. Schürer,Jouzas Vasiliauskas,Marcin Pilarczyk,Behrouz Shamsaei,Mehdi Fazel,Yan Ren,Wen Niu,Nicholas A. Clark,Shana White,Naim Al Mahi,Lixia Zhang,Michal Kouril,John F. Reichard,Siva Sivaganesan,Mario Medvedovic,Jaroslaw Meller,Rick J. Koch,Marc R. Birtwistle,Ravi Iyengar,Eric A. Sobie,Evren U. Azeloglu,Julia A. Kaye,Jeannette Osterloh,Kelly Haston,Jaslin Kalra,Steve Finkbiener,Jonathan Z. Li,Pamela Milani,Miriam Adam,Renan Escalante-Chong,Karen Sachs,Alexander LeNail,Divya Ramamoorthy,Ernest Fraenkel,Gavin Daigle,Uzma Hussain,Alyssa Coye,Jeffrey D. Rothstein,Dhruv Sareen,Loren Ornelas,Maria G. Banuelos,Berhan Mandefro,Ritchie Ho,Clive N. Svendsen,Ryan G. Lim,Jennifer Stocksdale,Malcolm Casale,Terri G. Thompson,Jie Wu,Leslie M. Thompson,Victoria Dardov,Vidya Venkatraman,Andrea Matlock,Jennifer E. Van Eyk,Jacob D. Jaffe,Malvina Papanastasiou,Aravind Subramanian,Todd R. Golub,Sean D. Erickson,Mohammad Fallahi-Sichani,Marc Hafner,Nathanael S. Gray,Jia-Ren Lin,Caitlin E. Mills,Jeremy L. Muhlich,Mario Niepel,Caroline E. Shamu,Elizabeth H. Williams,David Wrobel,Peter K. Sorger,Laura M. Heiser,Joe W. Gray,James E. Korkola,Gordon B. Mills,Mark A. LaBarge,Mark A. LaBarge,Heidi S. Feiler,Mark A. Dane,Elmar Bucher,Michel Nederlof,Damir Sudar,Sean M. Gross,David Kilburn,Rebecca Smith,Kaylyn Devlin,Ron Margolis,Leslie Derr,Albert Lee,Ajay Pillai +107 more
TL;DR: The LINCS program focuses on cellular physiology shared among tissues and cell types relevant to an array of diseases, including cancer, heart disease, and neurodegenerative disorders.
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Crosstalk between invadopodia and the extracellular matrix.
Shinji Iizuka,Ronald P. Leon,Kyle P. Gribbin,Ying Zhang,Jose Navarro,Rebecca Smith,Kaylyn Devlin,Lei G. Wang,Summer L. Gibbs,James E. Korkola,Xiaolin Nan,Sara A. Courtneidge +11 more
TL;DR: 3D and high-density fibrillar collagen culture is used to demonstrate that native collagen-I, but not a form lacking the telopeptides, stimulated Tks5-dependent growth, which was dependent on the DDR collagen receptors and reveal the invadopodium to be a spatially complex structure.
18
A LINCS microenvironment perturbation resource for integrative assessment of ligand-mediated molecular and phenotypic responses
Sean M. Gross,Mark A. Dane,Rebecca Smith,Kaylyn Devlin,Ian McLean,Daniel S. Derrick,Caitlin E. Mills,Kartik Subramanian,Alexandra B K London,Denis Torre,Cemal Erdem,Nicholas J. Lyons,Ted Natoli,Sarah Pessa,Xiaodong Lu,James Mullahoo,Jonathan Z. Li,Miriam Adam,Brook T. Wassie,Moqing Liu,David Kilburn,Tiera Liby,Elmar Bucher,Crystal Sanchez-Aguila,Kenneth Daily,Larsson Omberg,Yunguan Wang,Connor A. Jacobson,Clarence Yapp,Mirra Chung,Dusica Vidovic,Yiling Lu,Stephan C. Schürer,Albert Lee,Ajay S. Pillai,Aravind Subramanian,Malvina Papanastasiou,Ernest Fraenkel,Heidi S. Feiler,Gordon B. Mills,Jake Jaffe,Avi Ma'ayan,Marc R. Birtwistle,Peter K. Sorger,James E. Korkola,Joe W. Gray,Laura M. Heiser +46 more
TL;DR: In this article, the authors generated a comprehensive dataset that catalogs the transcriptional, proteomic, epigenomic and phenotypic responses of MCF10A mammary epithelial cells after exposure to the ligands EGF, HGF, OSM, IFNG, TGFB and BMP2.
An altered extracellular matrix–integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells
Sarah Hernandez,Ryan G. Lim,Tarik S. Onur,Mark A. Dane,Rebecca Smith,Keona Q. Wang,Grace H. Jean,Andrea M. Reyes-Ortiz,Kaylyn Devlin,Ricardo Miramontes,Jie Wu,Malcolm Casale,David Kilburn,Laura M. Heiser,James E. Korkola,David Van Vactor,Juan Botas,Katherine L. Thompson-Peer,Leslie M. Thompson +18 more
TL;DR: In this article , the authors used HD patient-derived induced pluripotent stem cell (iPSC) modeling to study the ECM-ITG interface in astrocytes and brain microvascular endothelial cells and found ECM dysregulation in human iPSC-derived cells that may contribute to the dysfunction of the BBB in HD.
6
Crosstalk between invadopodia and the extracellular matrix
Shinji Iizuka,Ronald P. Leon,Kyle P. Gribbin,Ying Zhang,Jose Navarro,Rebecca Smith,Kaylyn Devlin,Lei G. Wang,Summer L. Gibbs,James E. Korkola,Xiaolin Nan,Sara A. Courtneidge +11 more
TL;DR: High-density fibrillar collagen culture is used to demonstrate that native type I collagen, but not a form lacking the telopeptides, stimulated Tks5-dependent growth, which was dependent on the DDR collagen receptors, and reveal the invadopodium to be a spatially complex structure.