Kay Perry
Argonne National Laboratory
49 Papers
194 Citations
Kay Perry is an academic researcher from Argonne National Laboratory. The author has contributed to research in topics: Biology & Chemistry. The author has an hindex of 20, co-authored 41 publications. Previous affiliations of Kay Perry include University of Pennsylvania & Northwestern University.
Chat about Author
Papers
Structural basis of agrin–LRP4–MuSK signaling
Yinong Zong,Bin Zhang,Shenyan Gu,Kwangkook Lee,Jie Zhou,Guorui Yao,Dwight Figueiredo,Kay Perry,Lin Mei,Rongsheng Jin +9 more
TL;DR: It is shown that the tetrameric complex is essential for neuronal agrin-induced acetylcholine receptor (AChR) clustering and represent a novel mechanism for activation of receptor tyrosine kinases.
Structure of a eukaryotic SWEET transporter in a homotrimeric complex
Yuyong Tao,Lily S. Cheung,Shuo Li,Shuo Li,Joon-Seob Eom,Li Qing Chen,Yan Xu,Kay Perry,Wolf B. Frommer,Liang Feng +9 more
TL;DR: Structural and biochemical analyses show OsSWEET2b in an apparent inward (cytosolic) open state forming homomeric trimers, valuable for understanding the transport mechanism of eukaryotic SWEETs and may be useful for engineering sugar flux.
Attachment site recognition and regulation of directionality by the serine integrases
TL;DR: The structure of the C-terminal domains of a serine integrase bound to an attP DNA half-site leads directly to models for understanding how the integrase-bound attP and attB sites differ, why these enzymes preferentially form attP × attB synaptic complexes to initiate recombination, and how attL × attR recombination is prevented.
84
Structure of the full-length Clostridium difficile toxin B.
Peng Chen,Kwok-Ho Lam,Zheng Liu,Frank A. Mindlin,Baohua Chen,Craig B. Gutierrez,Lan Huang,Yongrong Zhang,Therwa Hamza,Hanping Feng,Tsutomu Matsui,Mark E. Bowen,Kay Perry,Rongsheng Jin +13 more
TL;DR: A 3.87-A-resolution crystal structure of TcdB holotoxin is reported that captures a unique conformation of TccB at endosomal pH that may facilitate modulation of TCDB activity in response to environmental and cellular cues during intoxication.
Structural basis for specificity in the poxvirus topoisomerase.
TL;DR: The crystal structures of the smallpox virus topoisomerase enzyme bound both covalently and non-covalently to a specific DNA sequence have been presented in this paper.
53