Katy Ong
University of Pennsylvania
5 Papers
Katy Ong is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Internal medicine & Coagulopathy. The author has an hindex of 3, co-authored 3 publications.
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Papers
Architecture and dynamic remodelling of the septin cytoskeleton during the cell cycle
TL;DR: This work provides an unparalleled view of septin structures within cells and defines their remodeling dynamics during the cell cycle.
The (dys)functional extracellular matrix
Benjamin R. Freedman,Nathan D. Bade,Corinne N. Riggin,Sijia Zhang,Philip Haines,Katy Ong,Paul A. Janmey +6 more
TL;DR: This review provides an overview of the structural, compositional, and mechanical properties of the ECM that instruct cell behaviors and how it may vary across normal and diseased tissues in response to mechanical and biochemical cues.
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Multiple feedback mechanisms fine-tune Rho signaling to regulate morphogenetic outcomes
TL;DR: A distinctive morphological process of cell alignment in the Drosophila embryonic epithelium reveals that multiple feedback mechanisms in the Rho pathway can fine-tune tissue morphology during development.
Systemic coagulopathy promotes host lethality in a new Drosophila tumor model
TL;DR: In this paper , the authors demonstrate that a new tumor model in Drosophila provokes phenotypes that resemble coagulopathies observed in patients and show that rescuing coagulation by depleting a tumor-produced clotting factor improves survival of tumor-bearing flies, despite the fact that flies have an open (non-vascular) circulatory system.
8
Systemic coagulopathy drives host lethality in a new Drosophila tumor model
TL;DR: It is demonstrated that rescuing coagulopathy improves survival of tumor-bearing flies, despite the fact that flies have an open circulatory system, and establishes a platform for identifying alternative mechanisms by which tumor-driven coagULopathy triggers early mortality.