Katsuo Wada
11 Papers
108 Citations
Katsuo Wada is an academic researcher. The author has contributed to research in topics: Renal function & Kidney. The author has an hindex of 6, co-authored 11 publications.
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Papers
Oxygen radical scavengers and renal protection by indapamide diuretic in salt-induced hypertension of Dahl strain rats.
Yoshio Uehara,Yukari Kawabata,Hiroaki Shirahase,Katsuo Wada,Yukiko Hashizume,Shigeyoshi Morishita,Atsushi Numabe,Junichi Iwai +7 more
TL;DR: Results indicate that indapamide has antioxidant properties, and in addition to blood pressure reduction, such radical scavenging effects may contribute to its beneficial effects on renal function in vivo.
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Radical Scavenging Properties of Indapamide and Renal Protection in Dahl Salt-Sensitive Rats
Yoshio Uehara,Yukari Kawabata,Hiroaki Shirahase,Katsuo Wada,Yukiko Hashizume,Shigeyoshi Morishita,Atsushi Numabe,Junichi Iwai,Hiroaki Matsuoka,Tsuneaki Sugimoto +9 more
TL;DR: The evidence suggests that the diuretic indapamide exhibits radical scavenging effects on the kidney which may contribute to attenuating the renal injuries seen in salt-induced hypertension in Dahl S rats.
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Patent
Indolyl or indolinyl derivatives and medicinal use thereof as ACAT or lipid peroxidation inhibitors
Shoji Kamiya,Hiroaki Shirahase,Hiroshi Matsui,Shohei Nakamura,Katsuo Wada +4 more
- 30 Sep 1996
TL;DR: A heterocyclic derivative of the formula (I) is described in this paper, where each symbol is defined in the specification, and pharmaceutically acceptable salts thereof exhibit superior ACAT inhibitory activity and lipoperoxidation inhibitory action in mammals.
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Protective effect of the calcium antagonist NKY-722 against renal and arterial injuries in Dahl salt-sensitive rats.
Hiroaki Shirahase,Yoshio Uehara,Katsuo Wada,Hisanobu Shimaji,Toshihiko Ishimitsu,Yukiko Hashizume,Mamoru Kanda,Shohei Nakamura +7 more
TL;DR: NKY-722 improved the renal dysfunction, and reduced glomerular, renal and cerebral arterial injuries in Dahl-S rats, and is probably related to the effect on eicosanoid metabolism.
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Preventive Effect of Iganidipine on Renal and Cerebral Injuries in Salt-Induced Hypertension
TL;DR: Iganidipine completely prevented hypertensive death at the SHD and tended to increase the survival at the NHD and MHD, and reduced glomerulosclerosis and renal arterial and tubular injuries in a dose-dependent manner.
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