Katsumi Fujimoto
Hiroshima University
8 Papers
100 Citations
Katsumi Fujimoto is an academic researcher from Hiroshima University. The author has contributed to research in topics: Circadian rhythm & CLOCK. The author has an hindex of 7, co-authored 8 publications.
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Papers
Dec1 and Dec2 are regulators of the mammalian molecular clock
Sato Honma,Takeshi Kawamoto,Yumiko Takagi,Katsumi Fujimoto,Fuyuki Sato,Mitsuhide Noshiro,Yukio Kato,Ken-ichi Honma +7 more
TL;DR: Dec1 and Dec2 are regulators of the mammalian molecular clock, and form a fifth clock-gene family that repressed Clock/Bmal1-induced transactivation of the mouse Per1 promoter through direct protein–protein interactions with Bmal1 and/or competition for E-box elements.
708
Basic Helix-loop-helix Protein DEC1 Promotes Chondrocyte Differentiation at the Early and Terminal Stages
Ming Shen,Eri Yoshida,Weiqun Yan,Takeshi Kawamoto,Ketut Suardita,Yasuhiko Koyano,Katsumi Fujimoto,Mitsuhide Noshiro,Yukio Kato +8 more
TL;DR: DDEC1 is the first transcription factor that can promote both chondrogenic differentiation and terminal differentiation in cells exposed to transforming growth factor-β and insulin.
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Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP.
Mitsuhide Noshiro,Takeshi Kawamoto,Masae Furukawa,Katsumi Fujimoto,Yuzo Yoshida,Eri Sasabe,Shinichi Tsutsumi,Taizo Hamada,Sato Honma,Ken-ichi Honma,Yukio Kato +10 more
TL;DR: DEC2, but not DEC1, works as a direct output mediator that transmits the circadian signals to the hepatic functions, including the CYP7A, CYP8B, and CYP51 expression.
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Anti-membrane-bound transferrin-like protein antibodies induce cell-shape change and chondrocyte differentiation in the presence or absence of concanavalin A.
Ryo Oda,Ketut Suardita,Katsumi Fujimoto,Haiou Pan,Weiqun Yan,Atsushi Shimazu,Hideaki Shintani,Yukio Kato +7 more
TL;DR: It is suggested that the crosslinking of MTf changes the cell shape and induces chondrogenic differentiation, the first identification of a plant lectin receptor involved in cell-shape changes and the differentiation of animal cells.
Effects of overexpression of membrane-bound transferrin-like protein (MTf) on chondrogenic differentiation in Vitro.
Ketut Suardita,Katsumi Fujimoto,Ryo Oda,Atsushi Shimazu,Kazuko Miyazaki,Takeshi Kawamoto,Yukio Kato +6 more
TL;DR: The findings suggest that the expression of MTf on the cell surface facilitates the differentiation of prechondrogenic cells, although MTf overexpression alone seems to be insufficient to commit pluripotent mesenchymal cells to the chondrocyte lineage.
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