Katja Tummler
Humboldt University of Berlin
10 Papers
9 Citations
Katja Tummler is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Cyclin & Cell cycle. The author has an hindex of 6, co-authored 10 publications.
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Papers
Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements.
Dan Davidi,Elad Noor,Wolfram Liebermeister,Arren Bar-Even,Avi I. Flamholz,Katja Tummler,Uri Barenholz,Miki Goldenfeld,Tomer Shlomi,Ron Milo +9 more
TL;DR: The approach here characterizes the quantitative relationship between enzymatic catalysis in vitro and in vivo and offers a high-throughput method for extracting enzyme kinetic constants from omics data.
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The discrepancy between data for and expectations on metabolic models: How to match experiments and computational efforts to arrive at quantitative predictions?
Katja Tummler,Edda Klipp +1 more
TL;DR: This work states that there are theoretical concepts that could in principle deliver dynamic and quantitative descriptions of metabolism on a genome scale, but they dramatically lack information about the required parameter values and intracellular concentrations as well as computationally feasible parameterization methods.
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Value or waste: Perfusion imaging following radiofrequency ablation – early experience
Stefan F. Thieme,Janis L Vahldiek,Katja Tummler,Franz Poch,Ole Gemeinhardt,Bernhard Hiebl,Kai S. Lehmann,Bernd Hamm,Stefan M. Niehues +8 more
TL;DR: From this data CT perfusion analysis could be precise tool for measurement and visualization of ablated liver lesions and for immediate detection of incomplete ablation areas as well as discrimination of necrosis from vital tissue after RFA at high levels of significance.
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TCAIM controls effector T cell generation by preventing Mitochondria-Endoplasmic Reticulum Contact Site-initiated Cholesterol Biosynthesis
Christina Iwert,Stein J,Christine Appelt,Katrin Vogt,Rainer Rj,Katja Tummler,Muehle K,Katarina Stanko,Schumann J,Uebe D,K. Juerchott,Jan Lisec,Katharina Janek,Gille C,Textoris-Taube K,Sai S,Ansgar Petersen,Kuehl Aa,Edda Klipp,Christian Meisel,Birgit Sawitzki +20 more
TL;DR: The authors showed that TCAIM KI inhibited activation-induced changes in mitochondrial morphology and function and thus, CD4+ effector T cell formation, and showed that it also applies to CD8+ T cells and more importantly, delineate the molecular processes in mitochondria by which T CAIM controls effector cell differentiation.
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Roles of G1 cyclins in the temporal organization of yeast cell cycle - a transcriptome-wide analysis
TL;DR: The data and network analysis suggest mutual effects of cyclins with the transcriptional regulators SBF and MBF with an important role for temporal fine-tuning in Saccharomyces cerevisiae.