Kathrin Wagner
Novartis
21 Papers
446 Citations
Kathrin Wagner is an academic researcher from Novartis. The author has contributed to research in topics: Antibody & Immunoglobulin E. The author has an hindex of 15, co-authored 21 publications.
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Papers
Simultaneous production of interleukin 2, interleukin 4 and interferon-γ by activated human blood lymphocytes
TL;DR: IL 2, IL 4 and IFN‐γ accumulated in the Golgi system, which resulted in a characteristic morphology of the staining, eliminating problems with evaluation of background signals.
170
Interleukin-4 and interleukin-5 are rarely co-expressed by human T cells
Thomas Jung,Uwe Schauer,Christian H.L. Rieger,Kathrin Wagner,Karin Einsle,Christine Neumann,Christoph Heusser +6 more
TL;DR: It is concluded that the simultaneous production of IL‐4 and IL‐5 is a feature of repetitively activated human T cells after prolonged stimulation with a minimum of two restimulation cycles.
75
Generation of a recombinant mouse-human chimaeric monoclonal antibody directed against human carcinoembryonic antigen.
Norman Hardman,L. Lee Gill,Ronald F.J. De Winter,Kathrin Wagner,Melvyn Hollis,Felix Businger,Domenico Ammaturo,Franz Buchegger,Jean-Pierre Mach,Christoph Heusser +9 more
TL;DR: This anti‐CEA recombinant antibody should find application in in vivodiagnosis by immunoscintigraphy of human colonic carcinoma, and possibly also in therapy of the disease, overcoming some of the difficulties associated with the repeated use of non‐human immunoglobulins in human patients.
44
Inhibition of human airway sensitization by a novel monoclonal anti-IgE antibody, 17-9.
Klaus F. Rabe,Nikki Watson,Gordon Dent,Benita E. Morton,Kathrin Wagner,Helgo Magnussen,Christoph Heusser +6 more
TL;DR: It is concluded that allergen responses in sensitized human airways are dependent on IgE levels in the sensitizing serum while nonspecific (hyper)responsiveness depends on serum factors other than IgE.
41
Enhancement of human IL-4 activity by soluble IL-4 receptors in vitro.
TL;DR: It is shown that human recombinant sIL‐4R induced the formation of complexed IL‐4 in supernatants of activated T cells in a dose‐dependent manner as measured by newly developed enzyme‐linked immunosorbent assays.
41