Katherine E McDonell
Vanderbilt University Medical Center
25 Papers
29 Citations
Katherine E McDonell is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 5, co-authored 13 publications. Previous affiliations of Katherine E McDonell include Vanderbilt University.
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Papers
Cortical asymmetry in Parkinson's disease: early susceptibility of the left hemisphere.
Daniel O. Claassen,Katherine E McDonell,Manus J. Donahue,Shiv Rawal,Scott A. Wylie,Joseph S. Neimat,Hakmook Kang,Peter Hedera,David H. Zald,Bennett A. Landman,Benoit M. Dawant,Swati Rane +11 more
TL;DR: Evaluating hemispheric differences in estimated rates of atrophy in a large, well‐characterized cohort of PD patients found that the left nigrostriatal system appears more susceptible to early degeneration than the right.
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Pepinemab antibody blockade of SEMA4D in early Huntington’s disease: a randomized, placebo-controlled, phase 2 trial
Andrew Feigin,Elizabeth E. Evans,Terrence L. Fisher,John P. Leonard,Ernest S. Smith,Alisha M. Reader,Vikas Mishra,Richard Manber,Kimberly A Walters,Lisa Kowarski,David Oakes,Eric Siemers,Karl Kieburtz,Maurice Zauderer,Elise Kayson,Jody Goldstein,Richard L. Barbano,Karen Marder,Praveen Dayalu,H. Diana Rosas,Sandra K. Kostyk,John Kamholz,Brad A. Racette,Jee Bang,Daniel O. Claassen,Katherine E McDonell,Stewart A. Factor,Francis O. Walker,Clarisse Goas,Joanne Wojcieszek,Lynn A. Raymond,Jody Corey-Bloom,Victor Fung,Marissa Dean,M. Geshwind,Alexandra H Nelson,Samuel Frank,Kathrin LaFaver,Andrew P. Duker,Lawrence Elmer,Ali Samii,Yi-Han Lin,Sylvain Chouinard,Lauren Seeberger,Burton L. Scott,J. Boyd,N. McFarland,Erin Furr Stimming,Oksana Suchowersky,Claudia M. Testa,Karen O. Anderson +50 more
TL;DR: The SIGNAL trial as mentioned in this paper evaluated pepinemab, a semaphorin 4D (SEMA4D)-blocking antibody, for treatment of Huntington's disease (HD).
Taq1A polymorphism and medication effects on inhibitory action control in Parkinson disease.
Katherine E McDonell,Nelleke C. van Wouwe,Madaline B. Harrison,Scott A. Wylie,Daniel O. Claassen +4 more
TL;DR: It is reported that the direction of this effect depends on baseline levels of performance on inhibitory control tasks, which suggests that there may exist certain biologic determinants that contribute to these patient‐specific differences.
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Clinical Relevance of Orthostatic Hypotension in Neurodegenerative Disease
TL;DR: The pathophysiology of nOH with respect to the various α-synuclein-related neurodegenerative conditions is discussed and the associated clinical features, including gait instability, rapid eye movement behavior disorder, and hyposmia are highlighted.
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Risk-Taking Behaviors in Huntington's Disease.
Katherine E McDonell,Abagail E Ciriegio,Anna C Pfalzer,Lisa Hale,Shuhei Shiino,Heather Riordan,Sarah Moroz,R. Ryan Darby,Bruce E. Compas,Daniel O. Claassen +9 more
TL;DR: It is hypothesized that early pathological involvement of frontostriatal and mesolimbic networks may be important factors in the development of risk-taking behaviors in Huntington's disease.
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