Kateri A. Moore
Icahn School of Medicine at Mount Sinai
80 Papers
1.4K Citations
Kateri A. Moore is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 34, co-authored 80 publications. Previous affiliations of Kateri A. Moore include University of Minnesota & Baylor College of Medicine.
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Papers
Stem Cells and Their Niches
TL;DR: The stem cell niche concept is discussed, recent progress is highlighted, and important unanswered questions are identified.
1.7K
A Stem Cell Molecular Signature
Natalia Ivanova,John T. Dimos,Christoph Schaniel,Jason A. Hackney,Kateri A. Moore,Ihor R. Lemischka +5 more
TL;DR: This work determined global gene expression profiles for mouse and human hematopoietic stem cells and other stages of the hematopolietic hierarchy, which define key conserved regulatory pathways in this developmental system.
1.6K
Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions.
TL;DR: It is shown that the mechanism of expansion involves progressively lengthening periods between cell divisions, with long-term regenerative potential lost upon a fifth division, and suggests that HSCs accumulate discrete memory stages over their divisional history.
255
A molecular profile of a hematopoietic stem cell niche
Jason A. Hackney,Pierre Charbord,Brian P. Brunk,Christian J. Stoeckert,Ihor R. Lemischka,Kateri A. Moore +5 more
TL;DR: It is suggested that the AFT024 cell line represents a component of an in vivo stem cell niche, and this work undertook a functional genomics approach that combines extensive sequence mining of a subtracted cDNA library, high-density array hybridization and in-depth bioinformatic analyses.
231
Single adult human CD34+/Lin-/CD38- progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells
TL;DR: New insights are provided into the role of the microenvironment niche, which governs the earliest events in lymphoid development, and direct evidence that NK and B-lineage differentiation derive from a common lymphomyeloid hematopoietic progenitor under the same conditions is provided.
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